The Effect of Meal Composition on Blood Lipids



Status:Recruiting
Conditions:High Cholesterol
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - 65
Updated:4/21/2016
Start Date:October 2015
End Date:September 2016
Contact:Meena Shah, Ph.D.
Email:m.shah@tcu.edu

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The Effect of Meal Composition on Blood Lipid Concentrations

The purpose of this study is to see if a high-protein meal leads to a better postprandial
(after a meal) blood lipid profile compared to a high-monounsaturated meal.

The effect of a high-protein diet compared to a high-monounsaturated fat diet on fasting
lipids is controversial (1,2), In addition, these studies did not examine the effect of a
high-protein compared to a high-monounsaturated meal on postprandial lipid concentrations.
Postprandial lipid responses are important to examine since they are associated with heart
disease (3,4). In addition, most individuals in Western countries are in a postprandial
state for majority of the day. The present study will compare the effect of a high-protein
meal versus a high-monounsaturated fat meal on postprandial lipid responses.

Inclusion Criteria:

- Men and women ages 18-65 years.

Exclusion Criteria:

- Use of medications or supplements that affect lipid levels, body weight, or blood
glucose,

- following a weight loss diet,

- being a vegan,

- smoking,

- heavy alcohol use,

- pregnancy,

- lactation,

- severe depression,

- eating disorders,

- presence of liver, kidney, gastrointestinal, adrenal, or untreated thyroid disease,

- diabetes,

- lactose intolerance,

- documented mal-absorption, or

- bowel surgery that affects absorption.
We found this trial at
1
site
Fort Worth, Texas 76129
Principal Investigator: Meena Shah, Ph.D.
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from
Fort Worth, TX
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