Effects of Abatacept in Patients With Early Rheumatoid Arthritis



Status:Active, not recruiting
Conditions:Arthritis, Rheumatoid Arthritis
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:18 - Any
Updated:12/10/2017
Start Date:August 31, 2015
End Date:March 20, 2020

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A Phase 3B, Randomized, Double-Blind Clinical Trial to Evaluate the Efficacy and Safety of Abatacept SC in Combination With Methotrexate Compared to Methotrexate Monotherapy in Achieving Clinical Remission in Adults With Early Rheumatoid Arthritis Who Are Methotrexate Naive

The purpose of this study is to determine if abatacept is effective in the treatment of early
rheumatoid arthritis.

Subcutaneous (SC)

For more information regarding BMS clinical trial participation, please visit
www.BMSStudyConnect.com

Inclusion Criteria:

- Rheumatoid arthritis (RA) diagnosis less than 6 months

- CRP > 3 mg/L or Erythrocyte Sedimentation Rate (ESR) ≥ 28 mm/h

- At least 3 swollen and 3 tender joints

- Anti-citrullinated protein antibodies (ACPA) positive

Exclusion Criteria:

- At risk for tuberculosis

- Have acute infection

- Have chronic or recurrent bacterial or serious latent viral infection

- History of malignancies in the last 5 years except squamous skin, basal skin or
cervical carcinoma

- Previous treatment with any conventional or biologic Disease-modifying anti rheumatic
drugs (DMARD)
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Lincoln, Nebraska 68512
Phone: 402-420-1212
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Albuquerque, New Mexico 87102
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Albuquerque, New Mexico
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Arlington, Virginia 22205
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Bridgeport, Connecticut 06606
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Capital Federal, Buenos Aires
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Coeur D'alene, Idaho 83814
Phone: 208-765-5457
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Dallas, Texas 75231
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Danville, Virginia 24541
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Duncansville, Pennsylvania 16635
Phone: 814-693-0300
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Eagan, Minnesota 55121
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Freehold, New Jersey 07728
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Fullerton, California 92835
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Glendale, Arizona 85304
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Glendale, Wisconsin 53217
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Hagerstown, Maryland 21740
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Hickory, North Carolina 28601
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Hot Springs, Arkansas 71913
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Houston, Texas 77030
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Houston, Texas 77024
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Huntington Beach, California 92646
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Huntsville, Alabama 35801
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Jackson, Tennessee 38305
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Little Rock, Arkansas 72204
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Los Alamitos, California 90720
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Mesa, Arizona 85202
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Monroe, Louisiana 71203
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535 E 70th St
New York, New York 10021
(212) 606-1000
Hospital for Special Surgery Founded in 1863, Hospital for Special Surgery is the nation
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Oklahoma City, Oklahoma 73103
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Philadelphia, Pennsylvania 19152
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Phoenix, Arizona 85037
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Saint Louis, Missouri 63141
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Salisbury, North Carolina 28144
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Spokane, Washington 99204
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Sun City, Arizona 85351
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Tulsa, Oklahoma 74104
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Upland, California 91786
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Wilmington, North Carolina 28401
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1907 Tradd Ct
Wilmington, North Carolina 28401
(910) 799-5500
Phone: 910-815-6108
PMG Research of Wilmington PMG Research of Wilmington has two offices situated in a 1...
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Wyomissing, Pennsylvania 19610
Phone: 610-375-2466
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