Non Invasive Optical Imaging of WBC Count
| Status: | Completed |
|---|---|
| Conditions: | Blood Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 6/13/2018 |
| Start Date: | September 2015 |
| End Date: | September 2017 |
Non Invasive Optical Imaging of Capillaries Through the Nailfold for White Blood Cell Enumeration in Patients With Hematologic Malignancies
This research study is looking at a small device that measures white blood cell (WBC) counts
by being placed against the finger nail for participants who are undergoing stem cell
transplantation at Massachusetts General Hospital or have a hematologic malignancy and are
being seen as an outpatient.
by being placed against the finger nail for participants who are undergoing stem cell
transplantation at Massachusetts General Hospital or have a hematologic malignancy and are
being seen as an outpatient.
The objective of this study is to obtain data that would support the use of a method to
obtain WBC counts from images of small blood vessels called capillaries. These would be
obtained by pressing a small device on the surface of participants' finger nails to look
through the nail. These images will be obtained using a portable microscope called the
Dino-Lite Digital Microscope.
Having a non-invasive way to quickly measure WBC counts could be useful for a variety of
healthcare applications.
obtain WBC counts from images of small blood vessels called capillaries. These would be
obtained by pressing a small device on the surface of participants' finger nails to look
through the nail. These images will be obtained using a portable microscope called the
Dino-Lite Digital Microscope.
Having a non-invasive way to quickly measure WBC counts could be useful for a variety of
healthcare applications.
Inclusion Criteria:
- Patients with lymphoid malignancies or plasma cell dyscrasias who are admitted to the
Massachusetts General Hospital to undergo autologous stem cell transplantation or are
seen in the outpatient clinic
- Age ≥ 18 years
- Ability to understand and the willingness to sign a written informed consent document.
- Patients must have WBC ≥ 3000 / µl and ANC ≥ 1500 / µl at admission or their last
clinical visit to be enrolled.
Exclusion Criteria:
- History of allergic reactions attributed to compounds of similar chemical or biologic
composition of baby oil.
- Myelodysplasia
- Skin phototype < 4 in the Fitzpatrick scale.
We found this trial at
1
site
185 Cambridge Street
Boston, Massachusetts 02114
Boston, Massachusetts 02114
617-724-5200
Principal Investigator: Yi-Bin A. Chen, MD
Phone: 617-724-1124
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