A Multimodal Intervention to Address Sexual Dysfunction in Hematopoietic Stem Cell Transplant Survivors

Frequently survivors of stem cell transplantation report significant problems with their
sexual function that impacts their quality of life, mood, and their intimacy and relationship
with their partners. These issues can be very distressing to patients and their loved ones.
The study doctors want to know if the introduction of an intervention focused on improving
sexual function may improve a participant's overall care and quality of life.

The intervention includes a comprehensive assessment by a transplant clinician who is trained
in sexual dysfunction assessment to explore the reasons for sexual dysfunction and focus on
ways to improve the participant's symptoms. The study will use a series of questionnaires to
measure a participant's sexual function, quality of life, and mood.

The main purpose of this study is examine whether this intervention is feasible and helpful
for participants in terms of improving their symptoms and overall quality of life.

Inclusion Criteria:

- Adult patients (≥18 years) with hematologic malignancy who underwent an allogeneic HCT
at least 6 months prior to study enrollment.

- Ability to speak English or able to complete questionnaires with assistance required
from an interpreter or family member.

- Positive screen for sexual dysfunction that is causing distress based on the National
Comprehensive Cancer Network survivorship guidelines

Exclusion Criteria:

- Patients with relapsed disease post-HCT.

- Significant psychiatric or other co-morbid disease, which the treating clinician
believes prohibits the patient's ability to participate in the informed consent
procedures.