Investigation of Non-Invasive Outcomes Predictors in Patients Undergoing DBS for Movement Disorders



Status:Completed
Conditions:Neurology
Therapuetic Areas:Neurology
Healthy:No
Age Range:19 - Any
Updated:5/12/2018
Start Date:June 2014
End Date:December 1, 2016

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Investigation of Non-Invasive Outcomes Predictors in Patients Undergoing Deep Brain Stimulation for Movement Disorders

The purpose of the study is to determine if non-invasive measurements of brain waves from the
skin called electroencephalography (EEG) can predict whether the brain stimulator will help
your symptoms. Our goal is to obtain these brain wave measurements with patients both awake
and under general anesthesia, and then to evaluate which brain wave patterns are associated
with clinical improvement to determine if they could be useful for predicting whether the
surgery will work. If such predictive measures were established based upon the findings of
this study, they could be used in the future to improve surgical outcomes in the following
ways: (1) to help guide surgical targeting in the operating room awake or under anesthesia,
(2) to guide post-operative programming in clinic, and (3) and to develop potential feedback
systems for "automatic" programming of the brain stimulator system at home.


Inclusion Criteria:

1. Patients who elect to undergo deep brain stimulation as part of routine clinical care
for movement disorders (Parkinson's disease, essential tremor, dystonia, Tourette's
syndrome).

2. Adults, ages 19 and older

Exclusion Criteria:

1. Patients who are outside the age range for inclusion

2. Patients who are unable to consent to the research for cognitive or behavioral reasons

3. Patients who are medically too ill to participate, and

4. Patients who have their DBS programming at outside facilities
We found this trial at
1
site
1720 2nd Ave S
Birmingham, Alabama 35233
(205) 934-4011 
Phone: 205-934-0683
University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
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mi
from
Birmingham, AL
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