Study of NGM282 in Patients With Nonalcoholic Steatohepatitis (NASH)



Status:Recruiting
Conditions:Gastrointestinal, Hepatitis
Therapuetic Areas:Gastroenterology, Immunology / Infectious Diseases
Healthy:No
Age Range:18 - 75
Updated:6/7/2018
Start Date:May 2015
End Date:September 2019
Contact:Bryan Baxter
Email:bbaxter@ngmbio.com
Phone:650-243-5554

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A Phase 2, Randomized, Double-blind, Placebo-controlled, Parallel-group Multiple-center Study With Additional Open-label Single-blind and Placebo-controlled 24-Week Histology Cohorts to Evaluate the Safety, Tolerability, and Efficacy of NGM282 Administered for Up to 24 Weeks in Patients With Histologically Confirmed Nonalcoholic Steatohepatitis (NASH)

The purpose of this study is to determine the safety, tolerability, and efficacy of NGM282 in
patients with nonalcoholic steatohepatitis.


Inclusion Criteria:

- Males or females, between 18 and 75 years of age, inclusive

- Histologically confirmed NASH diagnosis

Exclusion Criteria:

- Clinically significant acute or chronic liver disease

- Prior liver transplantation
We found this trial at
18
sites
Kansas City, Missouri
1341
mi
from 91732
Kansas City, MO
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Chandler, Arizona
?
mi
from 91732
Chandler, AZ
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Charlottesville, Virginia
2208
mi
from 91732
Charlottesville, VA
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Chicago, Illinois
1728
mi
from 91732
Chicago, IL
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1223
mi
from 91732
Dallas, TX
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Denver, Colorado
818
mi
from 91732
Denver, CO
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Durham, North Carolina
2201
mi
from 91732
Durham, NC
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Germantown, Tennessee
?
mi
from 91732
Germantown, TN
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Lakewood Ranch, Florida
2151
mi
from 91732
Lakewood Ranch, FL
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Los Angeles, California
?
mi
from 91732
Los Angeles, CA
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Richmond, Virginia
2268
mi
from 91732
Richmond, VA
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Rollingwood, Texas
?
mi
from 91732
Rollingwood, TX
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San Antonio, Texas
1188
mi
from 91732
San Antonio, TX
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San Antonio, Texas
1188
mi
from 91732
San Antonio, TX
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San Diego, California
106
mi
from 91732
San Diego, CA
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Seattle, Washington
961
mi
from 91732
Seattle, WA
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Sydney, New South Wales
7514
mi
from 91732
Sydney,
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Tucson, Arizona
?
mi
from 91732
Tucson, AZ
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