Study of NGM282 in Patients With Nonalcoholic Steatohepatitis (NASH)



Status:Recruiting
Conditions:Gastrointestinal, Hepatitis
Therapuetic Areas:Gastroenterology, Immunology / Infectious Diseases
Healthy:No
Age Range:18 - 75
Updated:6/7/2018
Start Date:May 2015
End Date:September 2019
Contact:Bryan Baxter
Email:bbaxter@ngmbio.com
Phone:650-243-5554

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A Phase 2, Randomized, Double-blind, Placebo-controlled, Parallel-group Multiple-center Study With Additional Open-label Single-blind and Placebo-controlled 24-Week Histology Cohorts to Evaluate the Safety, Tolerability, and Efficacy of NGM282 Administered for Up to 24 Weeks in Patients With Histologically Confirmed Nonalcoholic Steatohepatitis (NASH)

The purpose of this study is to determine the safety, tolerability, and efficacy of NGM282 in
patients with nonalcoholic steatohepatitis.


Inclusion Criteria:

- Males or females, between 18 and 75 years of age, inclusive

- Histologically confirmed NASH diagnosis

Exclusion Criteria:

- Clinically significant acute or chronic liver disease

- Prior liver transplantation
We found this trial at
18
sites
Richmond, Virginia
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Richmond, VA
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Chandler, Arizona
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Chandler, AZ
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Charlottesville, Virginia
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Charlottesville, VA
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Chicago, Illinois
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Chicago, IL
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Dallas, TX
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Denver, Colorado
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Denver, CO
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Durham, North Carolina
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Durham, NC
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Germantown, Tennessee
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Germantown, TN
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Kansas City, Missouri
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Kansas City, MO
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Lakewood Ranch, Florida
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Lakewood Ranch, FL
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Los Angeles, California
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Los Angeles, CA
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Rollingwood, Texas
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Rollingwood, TX
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San Antonio, Texas
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San Antonio, TX
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San Antonio, Texas
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San Antonio, TX
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San Diego, California
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San Diego, CA
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Seattle, Washington
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Seattle, WA
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Sydney, New South Wales
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Sydney,
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Tucson, Arizona
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Tucson, AZ
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