Safety, Efficacy, Tolerability and Pharmacokinetics of AGN-223575 Ophthalmic Suspension in Patients With Dry Eye Disease



Status:Completed
Conditions:Ocular
Therapuetic Areas:Ophthalmology
Healthy:No
Age Range:18 - Any
Updated:4/6/2019
Start Date:June 2015
End Date:January 2016

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This study will evaluate the safety, efficacy, tolerability, and systemic pharmacokinetics of
3 different doses of topical ophthalmic AGN-223575 suspension compared to AGN-223575 vehicle
in patients with dry eye disease.


Inclusion Criteria:

- Signs and symptoms of dry eye disease

- Has used RESTASIS and/or artificial tears in both eyes twice a day for at least 60
days.

Exclusion Criteria:

- History of glaucoma, or ocular hypertension

- Diagnosis of ocular infection

- Use of contact lenses in the past 14 days or expected use during the study

- Use of any topical ophthalmic medications in the past 30 days

- Use of corticosteroids in the past 30 days.
We found this trial at
28
sites
Rapid City, South Dakota 57701
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Rapid City, SD
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Austin, Texas 78731
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Austin, TX
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Boston, MA
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Charleston, South Carolina 29414
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Charleston, SC
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Charlotte, NC
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Cincinnati, OH
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Colorado Springs, Colorado 80907
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Colorado Springs, CO
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Florence, South Carolina 29501
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Florence, SC
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Glendale, California 91203
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Glendale, CA
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High Point, North Carolina 27262
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High Point, NC
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Hoffman Estates, Illinois
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Hoffman Estates, IL
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Houston, Texas 77025
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Houston, TX
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Houston, Texas 77055
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Houston, TX
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Kansas City, Missouri 64154
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Kansas City, MO
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Lecanto, Florida 34491
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Lecanto, FL
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Lexington, Kentucky 40509
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Lexington, KY
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Morrow, Georgia 30260
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Morrow, GA
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New York, New York 10013
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New York, NY
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Newport Beach, California
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Newport Beach, CA
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Overland Park, Kansas 66211
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Overland Park, KS
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Phoenix, AZ
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Portland, OR
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Roswell, Georgia 30076
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Roswell, GA
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Saint Louis, Missouri 63131
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Saint Louis, MO
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San Antonio, Texas 78240
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San Antonio, TX
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Santa Ana, California 92705
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Santa Ana, CA
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Wantagh, New York 11793
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Wantagh, NY
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Washington, Missouri
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Washington, MO
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