Characterization of the Plasma Proteome Following Left Ventricular Assist Device Implantation



Status:Recruiting
Conditions:Cardiology, Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:21 - 90
Updated:4/21/2016
Start Date:October 2014
End Date:June 2016
Contact:Christina Aquilante, Pharm.D.
Email:Christina.Aquilante@ucdenver.edu
Phone:303-724-6126

Use our guide to learn which trials are right for you!

The purpose of this study is to characterize changes in the plasma proteome over time
following left ventricular assist device (LVAD) implantation.


Inclusion Criteria:

- Planned HeartMate II LVAD implantation

- Planned warfarin (goal INR, 2.0-3.0) and low-dose aspirin therapy post-LVAD placement

Exclusion Criteria:

- Prior history of mechanical circulatory support;

- Body weight < 110 lbs;

- Pre-existing hemolytic, bleeding, or immunologic disorders prior to LVAD
implantation;

- Severe aortic stenosis;

- Renal failure requiring dialysis;

- Hepatic dysfunction resulting in severe coagulopathies;

- Recent serious infection;

- Current need for prolonged ventilatory support;

- Prior organ transplantation;

- Blood transfusion within 14 days of the first planned study blood draw;

- Concomitant immunosuppressant or chemotherapeutic agents;

- Pregnant women;

- Decisionally challenged or prisoners;

- Unwilling to provide written informed consent
We found this trial at
1
site
13001 E 17th Pl
Aurora, Colorado 80045
(303) 724-5000
Phone: 303-724-6126
University of Colorado Anschutz Medical Campus Located in the Denver metro area near the Rocky...
?
mi
from
Aurora, CO
Click here to add this to my saved trials