Biomarkers in Samples From Younger Patients With Wilms Tumor
| Status: | Recruiting |
|---|---|
| Healthy: | No |
| Age Range: | Any |
| Updated: | 4/21/2016 |
| Start Date: | December 2011 |
Observational - Relationships Between Tumor-Associated Macrophages and Clinicopathological Factors in Wilms Tumor
This research study is studying biomarkers in tissue samples from younger patients with
Wilms tumor. Studying samples of tissue from patients with cancer in the laboratory may help
doctors identify and learn more about biomarkers related to cancer. It may also help doctors
predict how patients respond to treatment
Wilms tumor. Studying samples of tissue from patients with cancer in the laboratory may help
doctors identify and learn more about biomarkers related to cancer. It may also help doctors
predict how patients respond to treatment
PRIMARY OBJECTIVES:
I. To determine whether recruitment of tumor-associated macrophages is related to
clinicopathological factors in Wilms tumor (tumor stage, presence of vascular invasion,
tumor progression, and survival).
OUTLINE:
Paraffin-embedded specimens are analyzed for macrophage markers. Results of each sample are
then compared with patient's tumor stage, presence of vascular invasion, tumor progression,
and survival.
I. To determine whether recruitment of tumor-associated macrophages is related to
clinicopathological factors in Wilms tumor (tumor stage, presence of vascular invasion,
tumor progression, and survival).
OUTLINE:
Paraffin-embedded specimens are analyzed for macrophage markers. Results of each sample are
then compared with patient's tumor stage, presence of vascular invasion, tumor progression,
and survival.
Inclusion Criteria:
- Wilms tissue microarray samples provided by the Children's Oncology Group
We found this trial at
1
site
Monrovia, California 91016
Principal Investigator: Jessica J. Kandel, MD
Phone: 212-342-8585
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