Early Markers of Radiation-Induced Cardiac Injury in Hodgkin Lymphoma Treated With Radiation Therapy



Status:Active, not recruiting
Conditions:Lymphoma
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:8/1/2018
Start Date:April 2015
End Date:April 2022

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UFPTI 1431 - HL02: Investigating Early Markers of Radiation-Induced Cardiac Injury in Hodgkin Lymphoma Survivors Treated With Either Photon or Proton Radiation

The purpose of this study is to evaluate if radiation and chemotherapy treatment cause
cardiac abnormalities among survivors of Hodgkin's lymphoma.


Inclusion Criteria:

- Completed radiation and chemotherapy treatment for Hodgkin lymphoma involving the
mediastinum.

- Patient must be ≥ 18 years at time of consent.

Exclusion Criteria:

- Pregnant women at time of Cardiac MRI

- Contraindications to Cardiac MRI (contrast allergy, metal implants, medical devices)

- Glomerular filtration rate (GFR) < 30, unless approved by Radiologist (UF Health
Jacksonville Radiology Policy: Administration of Gadolinium-Based Contrast Agents).
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