AFIX to Improve HPV Vaccination



Status:Completed
Conditions:Vaccines
Therapuetic Areas:Immunology / Infectious Diseases
Healthy:No
Age Range:Any
Updated:2/25/2017
Start Date:April 2015
End Date:November 2016

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Adolescent AFIX: A Multi-state RCT to Increase Adolescent Vaccination by Facilitating Providers' Adoption of Best Practices

The University of North Carolina will test the effectiveness of the Centers for Disease
Control and Prevention's AFIX model for increasing HPV vaccination coverage among
adolescents. AFIX (Assessment, Feedback, Incentives and eXchange) consists of brief quality
improvement consultations that immunization specialists from state health departments
deliver to vaccine providers in primary care settings. Using immunization registry data, the
specialist evaluates the clinic's vaccination coverage and delivers education on best
practices to improve coverage. We will compare changes in HPV vaccination coverage before
and after consultations for high-volume pediatric and family medicine clinics across three
study conditions: traditional consultations (in-person group), virtual consultations
(webinar group), or no consultations (control group). In each participating state, 30
clinics will be randomly assigned to each study arm, for a total of 90 clinics per state, or
270 clinics overall. The primary objective of this study is to compare the change in
coverage for HPV vaccine initiation among 11-12 year old patients, from baseline to 6-month
follow-up. Secondarily, we will compare the change in coverage for other vaccines and age
groups.


Inclusion Criteria: Pediatric or family medicine clinics or practices in WA, IL, or MI
with

- at least 500 active records for patients, ages 11-17, in their states' immunization
information systems.
We found this trial at
4
sites
Olympia, Washington 98504
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Olympia, WA
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Chapel Hill, North Carolina 27599
(919) 962-2211
Univ of North Carolina Carolina’s vibrant people and programs attest to the University’s long-standing place...
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Chapel Hill, NC
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Lansing, Michigan 48913
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Lansing, MI
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Springfield, Illinois 62761
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Springfield, IL
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