Electrocautery vs Q-switch for Seborrheic Keratosis



Status:Not yet recruiting
Conditions:Dermatology
Therapuetic Areas:Dermatology / Plastic Surgery
Healthy:No
Age Range:18 - 65
Updated:1/9/2016
Start Date:August 2015
End Date:December 2016
Contact:Emily Poon, PhD
Email:nufsm-dermatology@northwestern.edu
Phone:312-695-4761

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Comparing the Efficacy and Risk of Adverse Events of Electrocautery Versus 532 nm Qswitched Neodymium-doped Yttrium Aluminium Garnet Laser for the Treatment of Flat Seborrheic Keratoses: A Randomized Control Trial

The primary objective of this study is to compare the efficacy and risk of adverse events of
electrocautery versus 532 nm Q-switched neodymium-doped yttrium aluminium garnet (Nd:YAG)
laser for the treatment of flat seborrheic keratoses.

This study is a pilot study designed to determine feasibility of these procedures.


Inclusion Criteria:

1. Subjects are Caucasian or Asian.

2. Subjects who are between 18-65 year olds.

3. Subjects have flat or macular seborrheic keratosis on dorsum of the hands and wrists,
extensor surfaces of the forearms. The diagnosis of flat seborrheic keratosis is
confirmed by two clinical dermatologists using routine clinical examination and
dermoscopy.

4. Subjects have Fitzpatrick skin type I-III.

5. Subjects are in good health.

6. Subjects have the willingness and the ability to understand and provide informed
consent and communicate with the investigator.

Exclusion Criteria:

1. History of keloids or hypertrophic scars.

2. Pregnant or lactating or intends to become pregnant in the next 3 months.

3. Active skin disease or skin infection in the treatment area.

4. Previous history of lidocaine allergy.

5. History of methemoglobinemia

6. Unable to understand the protocol or to give informed consent.

7. Any other condition that would, in the professional opinion of the investigator,
potentially affect response or participation in the clinical study or would pose as
an unacceptable risk to subject.
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