GnRH for Luteal Support in IVF/ICSI/FET Cycles

Conditions:Women's Studies, Infertility
Therapuetic Areas:Reproductive
Age Range:18 - 40
Start Date:November 2015
End Date:March 2019
Contact:Peter G McGovern, MD

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During IVF cycles an embryo is generally placed into the uterine cavity between 3 and 5 days
after fertilization. For a successful pregnancy to take place, that embryo must then implant
in the properly primed and staged endometrium, which subsequently must continue to develop to
accommodate the growing and maturing embryo and then fetus. This process is normally
regulated by hormonal interactions between the fetal, endometrial and luteal tissue. It has
been found that after IVF additional support for the endometrium with progesterone improves
implantation and subsequent live birth rates in IVF cycle . Recent data has shown that
additional supplementation with a single administration of a GnRH agonist around the time the
time of embryo transfer may further enhance these rates .

see above

Inclusion Criteria:

- women undergoing IVF/ICSI or frozen embryo transfers (FET) that less than 40 years

Exclusion Criteria:

- day 3 transfers
We found this trial at
Hasbrouck Heights, New Jersey 07604
Principal Investigator: Peter G. McGovern, MD
Hasbrouck Heights, NJ
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