A Rollover Study of ARRY-371797 in Patients With LMNA-Related Dilated Cardiomyopathy



Status:Active, not recruiting
Conditions:Cardiology, Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - Any
Updated:3/2/2019
Start Date:February 2015
End Date:February 2022

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This is a rollover study designed to investigate the safety and effectiveness of
investigational study drug ARRY-371797 in patients who previously received ARRY-371797 in a
study for patients with LMNA-related dilated cardiomyopathy sponsored by Array BioPharma and
may, in the Investigator's opinion, derive benefit from continued treatment.


Key Inclusion Criteria:

- Received ARRY-371797 as treatment for a genetic dilated cardiomyopathy secondary to
LMNA mutations in a clinical study sponsored by Array BioPharma.

- May, in the opinion of the Investigator, benefit from continued ARRY-371797 treatment.

- Additional criteria exist.

Key Exclusion Criteria:

- Discontinued treatment in the parent study for any reason other than study completion
or Sponsor termination of the study.

- Additional criteria exist.
We found this trial at
4
sites
3400 N Charles St
Baltimore, Maryland 21205
410-516-8000
Phone: 410-502-7310
Johns Hopkins University The Johns Hopkins University opened in 1876, with the inauguration of its...
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75 Francis street
Boston, Massachusetts 02115
(617) 732-5500
Principal Investigator: Calum MacRae, MD
Brigham and Women's Hosp Boston’s Brigham and Women’s Hospital (BWH) is an international leader in...
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Aurora, Colorado 80045
Phone: 303-724-2094
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Madison, Wisconsin 53713
Phone: 608-417-2141
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Madison, WI
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