Medicinal Nicotine for Preventing Cue Induced Craving
| Status: | Completed |
|---|---|
| Conditions: | Smoking Cessation, Tobacco Consumers |
| Therapuetic Areas: | Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 18 - 64 |
| Updated: | 12/20/2017 |
| Start Date: | September 2013 |
| End Date: | January 2015 |
The purpose of this study is to determine if changing the timeframe (relative to cue
presentation) at which the nicotine lozenge is given can attenuate the increase in symptoms
of tobacco craving and withdrawal that occur when smokers are presented with smoking cues. In
this cross-over study, all subjects attend three laboratory sessions at which either nicotine
lozenge or placebo is given prior to presentation of smoking cues or after presentation of
smoking cues. The order in which the three conditions will be presented are randomized.
presentation) at which the nicotine lozenge is given can attenuate the increase in symptoms
of tobacco craving and withdrawal that occur when smokers are presented with smoking cues. In
this cross-over study, all subjects attend three laboratory sessions at which either nicotine
lozenge or placebo is given prior to presentation of smoking cues or after presentation of
smoking cues. The order in which the three conditions will be presented are randomized.
Inclusion Criteria:
- Smoking a minimum number of cigarettes per day
- General good health
Exclusion Criteria:
- unstable medical or psychiatric conditions
- history of severe motion sickness (due to virtual reality equipment used to present
cues)
- women who are pregnant or breast feeding
The investigators will evaluate if there are other reasons why someone may not participate
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