Leg Function and ADL After ALT Reconstruction for Head and Neck Cancer



Status:Recruiting
Conditions:Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:5/19/2016
Start Date:January 2014
End Date:January 2017
Contact:Rick Suggs
Phone:7737024036

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Does Harvesting an Anterolateral Thigh (ALT) Flap Impact Lower Extremity Function and Activities of Daily Living (ADL) in Patients Undergoing Reconstructive Surgery for Head and Neck Cancer

Anterolateral thigh (ALT) free flap tissue transfer is a commonly used method of head and
neck reconstruction after head and neck cancer removal. The procedure involves removing some
muscle, skin, and tissue from the thigh, and this may affect leg function. The purpose of
this study is to determine the impact of ALT on ambulation and activities of daily living
(ADLs)

The ALT flap may be harvested as a subcutaneous, fasciocutaneous, musculocutaneous, or
adipofascial flap. At our institution, three surgeons commonly use this method of free
tissue transfer to reconstruct such defects. In our experience, patients following harvest
of ALT flap have impairments in lower extremity function that result in decreased
independence with transfers, gait and ability to independently perform ADLs. Consequently,
these patients receive Physical and Occupational Therapy following surgery and a number of
patients go on to receive therapy in a rehabilitation facility and/or as an outpatient. A
number of studies have examined donor site morbidity and lower extremity function following
ALT flap harvest. These studies, however, are heterogeneous and primarily use patient
reported and non-standardized scales as outcome measures. Additionally, there is a paucity
of literature related to Physical Therapy and Occupational Therapy outcomes and intervention
with this patient population, despite frequent referral of these patients for post-surgical
therapy.

This investigation will utilize the Lower Extremity Functional Scale, the Functional
Independence Measure, dynamometry, video analysis of a single leg squat and walking speed in
an effort to better assess the affect of ALT harvesting on patients' functional capacity
post operatively. These tests are valid and reliable measures commonly utilized in Physical
Rehabilitation.

Inclusion Criteria:

1. Over age 18;

2. Head and neck cancer;

3. To undergo anterolateral thigh free tissue transfer for head and neck reconstruction

Exclusion Criteria:

1. Inability to ambulate independently prior to surgery;

2. Inability to negotiate stairs prior to surgery;

3. Inability to follow simple commands;

4. Inability to negotiate stairs prior to surgery;

5. Previous free flap harvest from either lower extremity
We found this trial at
1
site
5801 South Ellis Avenue
Chicago, Illinois 60637
 773.702.1234
Principal Investigator: Alexander Langerman, MD
Phone: 773-702-4036
University of Chicago One of the world's premier academic and research institutions, the University of...
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Chicago, IL
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