Alzheimer's Disease Genetics Study



Status:Recruiting
Conditions:Alzheimer Disease, Neurology
Therapuetic Areas:Neurology
Healthy:No
Age Range:Any
Updated:3/2/2019
Start Date:June 2002
End Date:July 2021
Contact:Study Coordinator
Email:alzstudy@iupui.edu
Phone:1-800-526-2839

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National Cell Repository for Alzheimer's Disease (NCRAD)

The purpose of the Alzheimer's Disease Genetics Study is to identify the genes that are
responsible for causing Alzheimer's Disease (AD). One of the ways in which the risk factor
genes for late onset AD can be investigated is by identifying and collecting genetic material
from families with multiple members diagnosed with AD or dementia.

The purpose of the Alzheimer's Disease Genetics Study is to help identify the genes that may
be responsible for causing Alzheimer's Disease (AD) by collecting genetic material from
families with multiple members diagnosed with AD. Qualifying families will have two living
blood-related individuals who have been diagnosed with or are showing symptoms of AD or
dementia. Local study sites are located all over the United States, and arrangements may be
made for eligible families who do not live near a participating site. The biological samples
and data from these families will be made available to qualified researchers, who must sign a
Materials Transfer Agreement (MTA) in order to protect the privacy rights of study
participants before receiving DNA and data.

Inclusion Criteria:

- Two living family members diagnosed with AD or other dementia with any age of onset

- Biological samples available

- Fresh blood, or

- Immortalized lymphoblastic cell lines, or

- 3-5 grams of frozen cerebral cortex; fixed samples are not accepted

Please note: this study does not include genetic counseling; because no personal
identifying information such as name or date of birth is attached to samples, results of
individual tests are not available to participants or family members.

Exclusion Criteria:

- Does not meet inclusion criteria

- Member of a family that was included in the National Institute of Mental Health AD
Genetics Sib Pair collection
We found this trial at
1
site
9152 Kent Avenue
Multiple Locations, Indiana 46202
Phone: 800-526-2839
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from
Multiple Locations, IN
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