Triple Negative Breast Cancer and Germline Hereditary Breast and Ovarian Cancer Mutation Carrier Registry



Status:Recruiting
Conditions:Breast Cancer, Ovarian Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:Any
Updated:10/13/2018
Start Date:March 2011
End Date:March 2022
Contact:Carolyn Lehn
Email:clehn@kumc.edu
Phone:(913) 588-6079

Use our guide to learn which trials are right for you!

PROspective Evaluation of GErmline Mutations, Cancer Outcome and Tissue Biomarkers: A Registry for Patients With Triple Negative Breast Cancer and Germline Mutations

PROGECT is a registry for patients with Triple Negative breast cancer (TNBC) or patients who
have an identified germline mutations (such as a mutation on the BRCA1 or BRCA2 genes).

This study is being done to collect cancer-related information from patients with triple
negative breast cancer and patients with hereditary genetic mutations. This information will
help us better understand the link between genetic changes and cancer outcome in patients
with triple negative breast cancer.

Inclusion criteria include:

Triple Negative Breast Cancer

- ER/PR <10% and HER negative per current ASCO/CAP guidelines

- Stages I-IV

- Any age at diagnosis

- Patient must be within 5 years of diagnosis

- Eligible regardless of genetic testing status

- Genetic testing recommended for patients meeting NCCN and Medicare guidelines

AND/OR

Germline mutation Carriers

- Patients with deleterious or uncertain mutations in HBOC genes (BRCA, PTEN, P53,
-PALB2 etc) are eligible regardless of type/site of cancer

- Healthy patients harboring mutations also eligible

- There is no time limit from the time of diagnosis of cancer and enrollment.

- Eligible regardless of personal history of cancer

Exclusion Criteria include:

Triple Negative Breast Cancer -Patient is not within five years of diagnosis

Germline mutation Carriers:

-Patient only carries a HBOC mutation that is classified as "polymorphism" of "favor
polymorphism"
We found this trial at
13
sites
Overland Park, Kansas 66215
Phone: 913-498-7892
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Hays, Kansas 67601
Phone: 785-623-5761
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Hays, KS
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Independence, Missouri 64057
Phone: 816-698-8249
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Independence, MO
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Kansas City, Kansas 66112
Phone: 913-328-3206
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Kansas City, KS
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2301 Holmes
Kansas City, Missouri 64108
816-404-1000
Phone: 816-404-4093
Truman Medical Center Located in the heart of downtown Kansas City, TMC Hospital Hill is...
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Kansas City, MO
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Kansas City, Missouri 64131
Phone: 816-823-6640
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Kansas City, MO
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2316 E Meyer Blvd
Kansas City, Missouri 64132
(816) 276-4000
Phone: 816-276-4000
Research Medical Center Research Medical Center offers hospital and health clinic services across three Kansas...
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Kansas City, MO
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Kansas City, Missouri 64154
Phone: 816-584-4879
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Kansas City, MO
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Lee's Summit, Missouri 64064
Phone: 816-350-5825
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Lee's Summit, MO
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5721 W 119th St
Overland Park, Kansas 66209
(913) 498-6000
Phone: 913-498-7892
Menorah Medical Center Menorah Medical Center (MMC), a full-service, acute care hospital located on the...
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Overland Park, KS
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Overland Park, Kansas 66210
Phone: 913-234-0459
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Overland Park, KS
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Salina, Kansas 67401
Phone: 785-452-7038
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Salina, KS
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Westwood, Kansas 66205
Phone: 913-588-6079
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Westwood, KS
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