Treating Alzheimer's and Dementia With D-ribose

Clinical experience and the pathophysiology of Alzheimer's, including neuronal insulin
resistance, suggests that ribose improves clinical outcomes. This study will add ribose 5 gm
3 X day for 8 weeks to monitor outcomes in a pilot study.

Inclusion Criteria:

- A diagnosis of Alzheimer's and/or dementia with a Mini Mental Status Exam ( MMSE)
score over 12 or being ambulatory and able to travel outside the home with
assistance.

- Must have a caregiver living with them.

Exclusion Criteria:

- Overt and severe causes of secondary dementia such as metastatic brain cancers, or
severe overt infectious encephalopathies or severe autoimmune illness.

- Also, severe life threatening illnesses which would make them unlikely to be alive
after 6-12 months.