OCT Angiography in Wet AMD
| Status: | Recruiting |
|---|---|
| Conditions: | Ocular |
| Therapuetic Areas: | Ophthalmology |
| Healthy: | No |
| Age Range: | 50 - 100 |
| Updated: | 4/17/2018 |
| Start Date: | September 2014 |
| End Date: | December 2020 |
| Contact: | Omkar Thaware, B Optom, MSVS |
| Email: | thaware@ohsu.edu |
| Phone: | 503-494-7398 |
Optical Coherence Tomography Angiography in Neovascular Age-related Macular Degeneration
The primary goals of this study are to use optical coherence tomography (OCT) angiography
(blood vessel mapping) to:
1. diagnose the presence of new blood vessels in wet age-related macular degeneration (AMD)
2. evaluate patients undergoing treatment for wet AMD
3. determine if reduced flow to the choroid is a risk factor for developing wet AMD.
(blood vessel mapping) to:
1. diagnose the presence of new blood vessels in wet age-related macular degeneration (AMD)
2. evaluate patients undergoing treatment for wet AMD
3. determine if reduced flow to the choroid is a risk factor for developing wet AMD.
Inclusion Criteria (Groups with wet AMD):
- Adults aged 50 and older with clinical findings of treatment-naïve (never treated)
neovascular AMD with active new blood vessel growth confirmed by clinical testing will
be considered
Inclusion Criteria (Group with healthy eyes)
- No evidence of retinal disease
- Refractive error greater than +3.00 diopters or -7.00 diopters (glasses Rx)
- No recent eye surgery in the last 4 months
- No significant cataract to interfere with the quality of the imaging
Exclusion Criteria (All Groups):
- Inability to give informed consent
- Significant kidney disease
- Blood pressure greater than 180/110
- Previous macular laser treatment
- Inability to maintain stable fixation during OCT imaging
- Visual acuity worse than 20/200
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