Antibiotic Prophylaxis for Urinary Catheter Removal After Radical Prostatectomy



Status:Terminated
Conditions:Prostate Cancer, Cancer, Urology, Urinary Tract Infections
Therapuetic Areas:Nephrology / Urology, Oncology, Other
Healthy:No
Age Range:18 - Any
Updated:7/27/2016
Start Date:July 2014
End Date:May 2016

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Trial Summary
Trial Overview
Inclusion Criteria
The aim of this study is to determine whether antibiotics prophylaxis at the time of urinary
catheter removal decreases the number of symptomatic urinary tract infections in patients
after radical prostatectomy. In addition, the investigators aim to determine whether
antibiotic prophylaxis is potentially harmful to patients (e.g. adverse reactions from
antibiotic use, resistant bacteria in the urine, Clostridium difficile infections etc.). The
investigators also aim to identify specific populations that may be at higher risk of
developing urinary tract infections with urinary catheter use after radical prostatectomy.


Inclusion Criteria:

- Subjects will include patients undergoing radical prostatectomy for prostate cancer.
Subjects will be randomized into control or treatment group.

Exclusion Criteria:

- Subjects with a history of adverse reaction to ciprofloxacin, or any other quinolone
will be excluded. Subjects being treated with tizanidine or with a history of
myasthenia gravis will be excluded. In addition, we will exclude patients with major
immediate post-operative complications after prostatectomy including significant
post-operative bleeding with known pelvic hematoma and known urine leak.
We found this trial at
1
site
Univ of Rochester Medical Center
601 Elmwood Avenue
Rochester, New York 14642
(585) 275-2100
Univ of Rochester Medical Center One of the nation's top academic medical centers, the University...
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Rochester, NY
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