A Study Investigating the Efficacy and Safety of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration
| Status: | Completed |
|---|---|
| Conditions: | Ocular |
| Therapuetic Areas: | Ophthalmology |
| Healthy: | No |
| Age Range: | 50 - Any |
| Updated: | 10/25/2018 |
| Start Date: | September 18, 2014 |
| End Date: | January 29, 2018 |
A Phase III, Multicenter, Randomized, Double-Masked, Sham-Controlled Study to Assess the Efficacy and Safety of Lampalizumab Administered Intravitreally to Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration
This study is a Phase III, double-masked, multicenter, randomized, sham injection-controlled
study evaluating the efficacy and safety of lampalizumab administered by intravitreal
injections in participants with geographic atrophy (GA) secondary to age-related macular
degeneration (AMD).
study evaluating the efficacy and safety of lampalizumab administered by intravitreal
injections in participants with geographic atrophy (GA) secondary to age-related macular
degeneration (AMD).
Inclusion Criteria:
- Well demarcated area(s) of GA secondary to AMD with no evidence of prior or active
choroidal neovascularization (CNV) in both eyes
Exclusion Criteria:
Ocular Exclusion Criteria: Study Eye
- History of vitrectomy surgery, submacular surgery, or other surgical intervention for
AMD
- Previous laser photocoagulation for CNV, diabetic macular edema, retinal vein
occlusion, and proliferative diabetic retinopathy
- Previous intravitreal drug delivery (intravitreal corticosteroid injection,
anti-angiogenic drugs, anti-complement agents, or device implantation) Ocular
Exclusion Criteria: Both Eyes
- GA in either eye due to causes other than AMD
- Previous treatment with eculizumab, lampalizumab and/or fenretinide
We found this trial at
77
sites
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University of Wisconsin In achievement and prestige, the University of Wisconsin–Madison has long been recognized...
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8411 North Run Medical Drive
Richmond, Virginia 23226
Richmond, Virginia 23226
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