Value of Patch Testing in Direct Diet Therapy for Eosinophilic Esophagitis



Status:Completed
Conditions:Gastrointestinal
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:18 - 90
Updated:11/22/2017
Start Date:August 2014
End Date:September 2017

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Trial Summary
Trial Overview
Inclusion Criteria

Efficacy of Allergy Patch Testing in Directed Dietary Therapy of Eosinophilic Esophagitis: A Pilot Study

Can allergy patch test (APT) predict of dietary therapy in patients with Eosinophilic
Esophagitis?


Inclusion criteria:

- Adults ages 18-90

- Patients with EoE, defined as dysphagia with histologic finding of greater than or
equal to 15 eosinophils per high powered field (eos per HPF) on index esophageal
biopsy

- Persistent symptoms and/or greater than or equal to 10 eos per HPF on esophageal
biopsy after at least 8 weeks of twice daily PPI therapy

Exclusion criteria:

- Patients with conditions known to be associated with esophageal eosinophilia,
including Crohn's disease, Churg-Strauss, achalasia, and hypereosinophilic syndrome

- Topical swallowed steroids within 8 weeks of study enrollment

- Dermatologic conditions precluding application of Finn chambers to the skin for APT

- Inability to read due to: Blindness, cognitive dysfunction, or English language
illiteracy
We found this trial at
1
site
The Mayo Clinic
Rochester, Minnesota 55905
Principal Investigator: Karthik Ravi, M.D.
Phone: 507-538-0367
?
mi
from
Rochester, MN
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