MEDication Focused Outpatient Care for Underutilization of Secondary Prevention



Status:Completed
Conditions:High Blood Pressure (Hypertension), High Cholesterol, Peripheral Vascular Disease, Diabetes
Therapuetic Areas:Cardiology / Vascular Diseases, Endocrinology
Healthy:No
Age Range:55 - Any
Updated:2/21/2019
Start Date:January 20, 2015
End Date:September 30, 2018

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The study tested whether a pharmacist-run cardiovascular risk service (CVRS) at the
University of Iowa can increase use of national standards of care in clinics

This project conducted a multicenter, cluster-randomized study utilizing a centralized CVRS
for medical offices with large geographic, racial and ethnic diversity to determine the
extent to which the CVRS model will be implemented. Twenty primary care offices were
randomized to either the CVRS arm or a usual care arm, and 18 continued in the study. Each
clinic enrolled 20-30 patients per office for a total of 402 subjects, of which 186
represented racial minorities.

Subjects in the intervention arm clinic had regular contact by phone, email or text with a
CVRS clinical pharmacist housed at the University of Iowa. The pharmacist communicated with
the subject, with the site clinical pharmacist and, as needed, with the site provider to
optimize both the subject's pharmaceutical regimen and lifestyle behaviors. The CVRS
intervention lasted for 12 months.

A complex algorithm was used to calculate the degree to which the subject's care and medical
regimen follows national guidelines for reducing the risk of developing cardiovascular risk.

Post-intervention telephone interviews are being conducted with 20 intervention subjects in
order to assess their experience with the intervention and barriers and facilitators to the
intervention.

Inclusion Criteria:

- English speakers age 55 or greater

- Must have a medical history of at least one of the following:

- Coronary artery disease

- Myocardial infarction

- Stroke

- Transient Ischemic Attack

- Atrial Fibrillation

- Systolic heart failure

- Peripheral vascular disease/claudication

- Carotid artery disease

- Diabetes with either: Low density lipoprotein (LDL) 100 or greater AND/OR systolic
blood pressure 140 or higher or diastolic blood pressure 90 or higher

Exclusion Criteria:

- Signs of acute angina, stroke, heart failure or renal failure

- Systolic blood pressure 200 or greater or diastolic blood pressure 115 or greater

- Significant hepatic disease, including: Cirrhosis, Hepatitis B or C infection, Alanine
Aminotransferase (ALT) or Aspartate Aminotransferase (AST) 3 times control or higher,
or total bilirubin 2.0 mg/dl or higher
We found this trial at
18
sites
101 Jessup Hall
Iowa City, Iowa 52242
(319) 335-3500
University of Iowa With just over 30,000 students, the University of Iowa is one of...
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Chapel Hill, North Carolina 27599
(919) 962-2211
University of North Carolina at Chapel Hill Carolina’s vibrant people and programs attest to the...
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Chapel Hill, NC
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Gainesville, Florida 32610
(352) 392-3261
University of Florida The University of Florida (UF) is a major, public, comprehensive, land-grant, research...
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Gainesville, FL
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201 Presidents Circle
Salt Lake City, Utah 84108
801) 581-7200
University of Utah Research is a major component in the life of the U benefiting...
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Salt Lake City, UT
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4502 Medical Drive
San Antonio, Texas 78284
(210) 567-7000
University of Texas Health Science Center at San Antonio The University of Texas Health Science...
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San Antonio, TX
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4202 E Fowler Ave
Tampa, Florida 33620
(813) 974-2011
University of South Florida The University of South Florida is a high-impact, global research university...
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Tampa, FL
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Amarillo, TX
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Buffalo, New York 14260
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Davenport, Iowa 52803
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Downers Grove, Illinois 60515
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Downers Grove, IL
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Houston, Texas 77030
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Houston, TX
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Madison, Wisconsin 53792
(608) 263-2400
University of Wisconsin In achievement and prestige, the University of Wisconsin–Madison has long been recognized...
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Milwaukee, Wisconsin 53216
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Milwaukee, Wisconsin 53210
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1801 N Broad St
Philadelphia, Pennsylvania 19122
(215) 204-7000
Temple University Temple University is many things to many people. A place to pursue life's...
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Pocatello, Idaho 83209
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Sioux City, IA
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Waterloo, IA
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