Supportive Care Intervention In Patients Hospitalized For Hematopoietic Stem Cell Transplantation (Shield)

This research study is evaluating the impact of early involvement of supportive care team
working with the transplant oncology team will have on the quality of life, symptoms, and
mood of patients undergoing stem cell transplantation.

The purpose of this research study is to find out whether introducing patients and families
undergoing stem cell transplantation to the palliative care team that specializes in symptom
management can improve the physical and psychological symptoms that patients and families
experience during hospitalization for stem cell transplantation.

The study will use a series of questionnaires to measure participant's and their caregivers'
quality of life, physical symptoms, and mood. Study questionnaires will be completed in the
hospital or clinic with assistance provided as needed

Inclusion Criteria:

- Patients Eligibility Criteria:

- Adult patients (≥18 years) with hematologic malignancy admitted to Massachusetts
General Hospital for HSCT are eligible for the study.

- Ability to speak English or able to complete questionnaires with minimal
assistance required from an interpreter or family member.

- Caregivers Eligibility Criteria:

- Adult caregivers (>18 years) of patients undergoing HSCT at MGH who agreed to
participate in study.

- A relative or a friend, identified by the patient who either lives with the
patient or has in-person contact with him or her at least twice per week.

- Ability to read questions in English or willing to complete questionnaires with
the assistance of an interpreter.

Exclusion Criteria:

- Patients with prior history of HSCT.

- Patients undergoing HSCT for a benign hematologic condition (myelodysplastic syndrome
(MDS) is not considered a benign hematologic condition and patients with MDS are
eligible for the study)

- Significant uncontrolled psychiatric disorder (psychotic disorder, bipolar disorder,
major depression) or other co-morbid disease (dementia, cognitive impairment), which
the treating clinician believes prohibits informed consent or participation in the
study.

- Patients enrolled on other supportive care intervention trials.