Evaluation of ETC-1002 in Patients With Hypercholesterolemia and Hypertension



Status:Completed
Conditions:High Blood Pressure (Hypertension), High Cholesterol
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - 80
Updated:3/31/2019
Start Date:June 2014
End Date:July 2015

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A Placebo-Controlled, Randomized, Double-Blind, Parallel Group Study to Evaluate the Efficacy and Safety of ETC-1002 in Patients With Hypercholesterolemia and Hypertension

This Phase 2 study will assess the efficacy and safety of ETC-1002 monotherapy versus placebo
in patients with hypercholesterolemia and hypertension.


Inclusion Criteria:

- Mean 24-hour ambulatory SBP greater than or equal to 130 mmHg

- or- Mean 24-hour ambulatory DBP greater than or equal to 80 mmHg

- Fasting LDL-C between 100 and 220 mg/dL

- Fasting triglycerides less than 400 mg/dL

- Body mass index (BMI) between 18 and 45 kg/m2

Exclusion Criteria:

- Known or suspected secondary hypertension or history of malignant hypertension

- Taking more than two anti-hypertension medications at the first visit

- History or current clinically significant cardiovascular disease

- History or current type 1 diabetes or type 2 diabetes
We found this trial at
35
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Fort Lauderdale, FL
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Auburn, ME
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Berlin, NJ
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Birmingham, AL
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Butte, MT
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Chandler, AZ
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Charleston, South Carolina 29412
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Charleston, SC
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Cincinnati, OH
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Cincinnati, OH
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DeLand, FL
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Downingtown, Pennsylvania 19335
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Downingtown, PA
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Endwell, NY
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Eugene, OR
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Gurnee, IL
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Hialeah, FL
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Houston, TX
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Indianapolis, IN
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Kenosha, WI
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Las Vegas, NV
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Madison, WI
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Olive Branch, Mississippi 38654
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Olive Branch, MS
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Paducah, KY
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Pembroke Pines, FL
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Pembroke Pines, FL
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Phoenix, AZ
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Salt Lake City, UT
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Simpsonville, SC
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Willoughby Hills, OH
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Wilmington, North Carolina 28401
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Wilmington, NC
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