Serial Therapeutic and Antifungal Monitoring Protocol

One blood culture and one set of T2clinical specimens will be collected at specified
intervals to monitor the clearance of Candida infection from the bloodstream.

Each T2 result will be compared to the companion blood culture result. The comparison will
determine if the presence of antifungal therapy inhibits blood culture and leads to an
incidence of blood culture false negative test results. The T2 result, which is not impacted
by the presence of antifungal therapy, can show that the pathogen is still present for some
additional period of time.

Inclusion Criteria:

- Subject or subject's authorized representative must be able to understand, read and
sign the study specific informed consent form after the nature of the study has been
fully explained to them.

- Subject is between 18-95 years of age

- Subject has a blood culture result that is positive for yeast within 36 hours of
enrollment

Exclusion Criteria:

- Subject has other co-morbid condition(s) that, in the opinion of the Investigator,
could limit the subject's ability to participate in the study or impact the scientific
integrity of the study

- All T2 Bio individual clinical research specimens contain < 3 ml of blood

- Use of any novel (i.e. not commercially available) drug compound within 30 days prior
to the collection of T2 Bio blood specimens.