A Prospective Randomized Controlled Clinical Trial of Standard Versus Goal-Directed Perioperative Fluid Management (GDT) for Patients Undergoing Radical Cystectomy

Status:	Active, not recruiting
Conditions:	Cancer, Cancer, Bladder Cancer
Therapuetic Areas:	Oncology
Healthy:	No
Age Range:	21 - Any
Updated:	12/23/2018
Start Date:	May 2014
End Date:	May 2019

The purpose of this study is to help us learn what is the best amount of fluid to give to
patients during bladder surgery in order to avoid delayed bowel function after surgery, which
could prolong hospital stay.

Inclusion Criteria:

- Adults (21 years old or greater) who are able to provide informed consent

- Patients who undergo an open, elective radical cystectomy

Exclusion Criteria:

- Patients with active atrial fibrillation or flutter, since the algorithm is not
accurate in case of cardiac arrhythmia

- Female patients who are pregnant (female patients of child-bearing potential must have
a negative serum pregnancy test ≤ 14 days prior to surgery or 15 to 30 days prior to
surgery with a negative urine pregnancy test the morning of surgery)

- Presence of ascites, because increased abdominal pressure interferes with EV1000
reading accuracy

- BMI > 45 or <17, because increased abdominal pressure interferes with EV1000 reading
accuracy

We found this trial at

sites

Memoral Sloan Kettering Westchester

Harrison, New York

Phone: 212-639-2680

from

Harrison, NY