Depression Screening in Patients With Lung Cancer



Status:Recruiting
Conditions:Lung Cancer, Cancer, Depression
Therapuetic Areas:Oncology, Psychiatry / Psychology
Healthy:No
Age Range:18 - Any
Updated:3/30/2013
Start Date:April 2006

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Maximizing Utilization of Depression Screening in Lung Cancer Patients: A Randomized Trial


RATIONALE: Screening tests may help doctors find depression in patients with lung cancer,
allow doctors to recommend treatment for depression, and improve the patient's quality of
life.

PURPOSE: This randomized clinical trial is studying how well depression screening works when
the results are or are not shared with patients with lung cancer and their doctor.


OBJECTIVES:

Primary

- Determine the impact of depression screening in patients with lung cancer when the
results of the screening are made available to the patient, the physician, both, or
neither on detection of depression, provision of depression treatment recommendations,
and the quality of the doctor-patient interaction from the patient's perspective.

Secondary

- Determine psychological and demographic subsets for the impact of depression screening
in these patients when the results of the screening are made available to the patient,
the physician, both, or neither on the detection of depression, provision of depression
treatment recommendations, and the quality of the doctor-patient interaction from the
patient's perspective.

OUTLINE: This is a multicenter, randomized, double-blind, single-blind, factorial study.
Patients are stratified according to participating center (Memorial Sloan-Kettering Cancer
Center vs University of Kentucky Markey Cancer Center). Patients are randomized to 1 of 4
screening arms.

- Arm I (control): Patients complete screening questionnaires about their mood and
experience with lung cancer once before and once after a visit with their physician.
Neither the patient nor physician receives the screening results before the visit.

- Arm II: Patients complete screening questionnaires as in arm I. Only the patient
receives the screening results before their visit with the physician; the physician
remains blinded to the results.

- Arm III: Patients complete screening questionnaires as in arm I. Only the physician
receives the screening results before their visit with the patient; the patient remains
blinded to the results.

- Arm IV: Patients complete screening questionnaires as in arm I. Both physician and
patient receive the screening results before the visit.

All patients and physicians are notified of the screening results before the patient leaves
the clinic. All patients are offered supportive counseling.

PROJECTED ACCRUAL: A total of 300 patients will be accrued for this study.

DISEASE CHARACTERISTICS:

- Diagnosis of lung cancer

- Prescreening distress thermometer score > 3

- Zung Self-Rating Depression Scale (ZSDS) score ≥ 44

- No ZSDS response indicating suicidality

PATIENT CHARACTERISTICS:

- Able to understand English

- No evidence of cognitive dysfunction that would impair giving consent

PRIOR CONCURRENT THERAPY:

- Not specified
We found this trial at
2
sites
800 Rose St
Lexington, Kentucky 40536
(859) 257-4488
Lucille P. Markey Cancer Center at University of Kentucky The Markey Cancer Center was founded...
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Lexington, KY
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1275 York Avenue
New York, New York 10065
212-639-2000
Memorial Sloan-Kettering Cancer Center Memorial Sloan-Kettering Cancer Center — the world's oldest and largest private...
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from
New York, NY
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