Comparing Pleth Variability Index (PVI) Measurements at Different Sensing Locations



Status:Recruiting
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:April 2014
End Date:December 2016
Contact:Maxime Cannesson, PhD
Email:mcanness@uci.edu
Phone:(714) 456-8869

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Comparing PVI Measurements at Different Sensing Locations

The purpose of this study is to assess the suitability of the ear and forehead as a better
site for measure of fluid responsiveness.

The aim of this study is to compare Pleth Variability Index (PVI) measurements at different
sensor locations in respect to signal quality, sensor fit to site location and fluid
responsiveness. PVI will be measured at 3 different sensor sites: the fingers, ear lobes and
forehead. The ability to predict fluid responsiveness will be analyzed using cardiac output
as the reference value.

Inclusion Criteria:

- 18 years of age or older

- Undergo any type of surgeries under general anesthesia in UCI Medical Center

- Mechanically ventilated during surgery

- Arterial line placement is preferred but not required

- Agree to sign the consent and HIPAA forms

Exclusion Criteria:

- Less than 18 years of age

- Pregnant women

- Refused to sign the consent and HIPAA forms

- Receive vasoactive medication prior to surgery

- Has these conditions: hypotension, hypothyroidism, moderate or poorly controlled
hypertension, chronic poorly-controlled diabetes, heart failure patients, and
patients with active airway flow obstruction, left ventricular dysfunction,
intra-cardiac shunts, right ventricular dysfunction, atrial fibrillation, arrhythmias

- patients with surgeries at or around site of sensor placement

- Subject has skin abnormalities affecting the digits such as psoriasis, eczema,
angioma, scar tissue, burn, fungal infection, substantial skin breakdown, nail polish
or acrylic nails that would prevent monitoring of SpO2 levels during the study
We found this trial at
1
site
101 The City Drive South
Orange, California 92868
714-456-7890
Principal Investigator: Maxime Cannesson, MD, PhD
Phone: 714-456-8869
University of California, Irvine Medical Center We are UC Irvine Health. We are a devoted...
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