Evaluation of Neuroinflammation in Children With Infantile Spasms



Status:Completed
Conditions:Other Indications, Metabolic
Therapuetic Areas:Pharmacology / Toxicology, Other
Healthy:No
Age Range:Any
Updated:11/9/2017
Start Date:March 2013
End Date:July 2017

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Trial Summary
Trial Overview
Inclusion Criteria

Neuroinflammation in Children With Infantile Spasms Measured With 11C-PK11195 Positron Emission Tomography: Response to ACTH

The purpose of this study was to investigate the presence of neuroinflammation in children
with infantile spasms using 11C-PK11195 positron emission tomography (PK PET) scan, and its
response to ACTH treatment by repeating the PK PET scan after treatment.


Inclusion Criteria:

- A clinical diagnosis of 'cryptogenic IS'

- Normal MRI

- No other neurological disorder

Exclusion Criteria:

- Abnormal MRI

- No anti-inflammatory medication 48 hrs prior to PK PET scans

- Parent/guardian unable to give written consent
We found this trial at
1
site
Children's Hospital of Michigan
3901 Beaubien St
Detroit, Michigan 48201
(313) 745-5437
Principal Investigator: Ajay Kumar, MD,PhD,DNB
Phone: 313-993-2605
Children's Hospital of Michigan Since 1886, the Children's Hospital of Michigan has been dedicated to...
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mi
from
Detroit, MI
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