Parkinstep: Automated PD Gait and Balance Assessment for Optimizing DBS



Status:Recruiting
Conditions:Parkinsons Disease
Therapuetic Areas:Neurology
Healthy:No
Age Range:21 - Any
Updated:2/7/2015
Start Date:February 2014
Contact:Elizabeth Brokaw, PhD
Email:ebrokaw@glneurotech.com
Phone:216-446-2453

Use our guide to learn which trials are right for you!

Changes in deep brain stimulation (DBS) settings can have a delayed effect on gait function,
which makes it impractical to optimize DBS for gait parameters in the clinic. Wearable
movement sensors could be used to assess gait impairment in the patient's home hours after
treatment adjustments are made in the clinic. This study aims to quantitatively evaluate the
effects of turning off deep brain stimulation on lower extremity and gait function over
three hours. This study will provide vital information about our patient worn system's
ability to detect changes in lower impairment over time, which could be used to assist with
DBS tuning for the lower extremities and gait in the future.


Inclusion Criteria:

- Diagnosis of idiopathic Parkinson's disease

- Age > 21

- Underwent DBS surgery targeting the subthalamic nucleus (STN)

- Bilateral or midline involvement when "off" DBS/medication state

- Clinical history of gait impairment or freezing of gait

Exclusion Criteria:

- "Parkinson's plus" syndrome, secondary, or atypical Parkinson's disease

- Underwent DBS surgery targeting the ventral intermediate (VIM)

- Unable to walk independent of a wheelchair (use of assistive devices, like a cane, is
okay for this study)

- Dementia (determined by a neuropsychological assessment).
We found this trial at
2
sites
Cleveland, Ohio 44106
?
mi
from
Cleveland, OH
Click here to add this to my saved trials
2600 Clifton Ave
Cincinnati, Ohio 45267
(513) 556-6000
University of Cincinnati The University of Cincinnati offers students a balance of educational excellence and...
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials