Immune Characterization of Subcutaneous Adipose Tissue
| Status: | Completed |
|---|---|
| Healthy: | No |
| Age Range: | 18 - 65 |
| Updated: | 9/8/2017 |
| Start Date: | February 2014 |
| End Date: | September 2017 |
The overall goal of this proposal is to characterize the immune cell profile of subcutaneous
abdominal adipose tissue in lean, overweight, obese and lipedema adults, and to evaluate
potential associations between different adipose tissue immune cell types and metabolic
profile.
abdominal adipose tissue in lean, overweight, obese and lipedema adults, and to evaluate
potential associations between different adipose tissue immune cell types and metabolic
profile.
Inclusion Criteria:
- Women of all races and ethnicity
- Age between 18 and 65 years
- Body Mass Index (BMI) ≥ 18.5 kg/m²
- Weight stable (+/- 3% during the last 2 months before enrollment)
- Women already scheduled for above mentioned procedures
Exclusion Criteria:
- Diabetes Mellitus
- Recent (<5 years) history of cancer (except in situ ductal breast carcinoma)
- Chemotherapy and/or radiation therapy within 4 months before enrollment
- Immune system diseases (i.e., autoimmune disorders, acquired immunodeficiency
syndrome)
- Pregnant or breastfeeding
- Take any medication that might affect immune function
- Severe organ dysfunction
- BMI <18.5 kg/m² or size of each breast is >600 grams, if scheduled for bilateral
breast reconstruction
We found this trial at
1
site
660 S Euclid Ave
Saint Louis, Missouri 63110
Saint Louis, Missouri 63110
(314) 362-5000
Principal Investigator: Samuel Klein, MD
Phone: 314-362-5001
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
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