Efficacy and Safety Study as Monotherapy of Satralizumab (SA237) to Treat NMO and NMOSD
| Status: | Active, not recruiting |
|---|---|
| Healthy: | No |
| Age Range: | 18 - 74 |
| Updated: | 3/2/2019 |
| Start Date: | August 2014 |
| End Date: | March 2019 |
A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy and Safety of SA237 as Monotherapy in Patients With Neuromyelitis Optica (NMO) and NMO Spectrum Disorder (NMOSD)
The objective of this study is to evaluate the efficacy, safety, pharmacodynamic,
pharmacokinetic and immunogenic profiles of SA237 in patients with NMO and NMOSD
pharmacokinetic and immunogenic profiles of SA237 in patients with NMO and NMOSD
Inclusion Criteria:
- 1. NMO or NMOSD
- 2. Age 18 to 74 years, inclusive at the time of informed consent.
Exclusion Criteria:
- 1. Pregnancy or lactation.
- 2. Evidence of other demyelinating disease or progressive multifocal
leukoencephalopathy (PML).
- 3. Known active infection (excluding fungal infections of nail beds or caries dentium)
within 4 weeks prior to baseline.
We found this trial at
27
sites
University of Kansas Medical Center The University of Kansas Medical Center serves Kansas through excellence...
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Wayne State University Founded in 1868, Wayne State University is a nationally recognized metropolitan research...
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Univ of Rochester Medical Center One of the nation's top academic medical centers, the University...
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1500 E Medical Center Dr
Ann Arbor, Michigan 48109
Ann Arbor, Michigan 48109
(734) 936-4000
University of Michigan Health System The University of Michigan is home to one of the...
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115 Mason Farm Road
Chapel Hill, North Carolina 27599
Chapel Hill, North Carolina 27599
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Chicago, Illinois 60637
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303 E Chicago Ave
Chicago, Illinois 60611
Chicago, Illinois 60611
(312) 503-8194
Northwestern University Feinberg School of Medicine Northwestern University Feinberg School of Medicine, founded in 1859,...
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University of Cincinnati The University of Cincinnati offers students a balance of educational excellence and...
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University of Texas Southwestern Medical Center UT Southwestern is an academic medical center, world-renowned for...
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University of California, Irvine Since 1965, the University of California, Irvine has combined the strengths...
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8550 Marshall Drive
Lenexa, Kansas 66214
Lenexa, Kansas 66214
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1150 Northwest 14th Street
Miami, Florida 33136
Miami, Florida 33136
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Milwaukee, Wisconsin 53215
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Thomas Jefferson University We are dedicated to the health sciences and committed to educating professionals,...
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417 North 11th Street
Richmond, Virginia 23298
Richmond, Virginia 23298
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