Active Bathing to Eliminate Infection (ABATE Infection) Trial
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Infectious Disease, Infectious Disease, Hospital |
| Therapuetic Areas: | Immunology / Infectious Diseases, Other |
| Healthy: | No |
| Age Range: | 12 - Any |
| Updated: | 1/20/2018 |
| Start Date: | April 2014 |
| End Date: | December 2019 |
Cluster-Randomized Controlled Trial of Hospitals to Reduce Healthcare-Associated Infections and Readmissions Through Routine Bathing With Antiseptic Soap and Targeted Use of Nasal Antibiotic Ointment (ABATE Infection Trial)
The ABATE Infection Project is a cluster randomized trial of hospitals to compare two quality
improvement strategies to reduce multi-drug resistant organisms and healthcare-associated
infections in non-critical care units. The two strategies to be evaluated are:
- Arm 1: Routine Care Routine policy for showering/bathing
- Arm 2: Decolonization Use of chlorhexidine as routine soap for showering or bed bathing
for all patients Mupirocin x 5 days if MRSA+ by history, culture, or screen
Note that enrolled "subjects" represents 53 individual HCA Hospitals (representing ~190
non-critical care units) that have been randomized.
improvement strategies to reduce multi-drug resistant organisms and healthcare-associated
infections in non-critical care units. The two strategies to be evaluated are:
- Arm 1: Routine Care Routine policy for showering/bathing
- Arm 2: Decolonization Use of chlorhexidine as routine soap for showering or bed bathing
for all patients Mupirocin x 5 days if MRSA+ by history, culture, or screen
Note that enrolled "subjects" represents 53 individual HCA Hospitals (representing ~190
non-critical care units) that have been randomized.
Inclusion Criteria:
- All HCA hospitals that reside in the United States
- Note: Unit of randomization is the hospital, but the participants are hospital units
Exclusion Criteria:
- Non-critical care units where chlorhexidine bathing or decolonization for MRSA+
non-critical care patients is routine
- Pediatric, peri-partum, rehabilitation, psychiatry, and BMT units
- Units with >30% cardiac or hip/knee orthopedic surgeries
- Unit average length of stay <2 days
- Patients <12 years-old
- Patients with known allergy to mupirocin or chlorhexidine
We found this trial at
52
sites
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Research Medical Center Research Medical Center offers hospital and health clinic services across three Kansas...
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North Suburban Medical Center North Suburban Medical Center has established a reputation as a facility...
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