High-field Brain Magnetic Resonance Spectroscopy
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Healthy Studies |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 1/19/2018 |
| Start Date: | November 2012 |
| End Date: | November 2018 |
Technical Developments for High-field Brain Magnetic Resonance Spectroscopy
Magnetic resonance spectroscopy (MRS) allows non-invasive measurement of the concentration of
up to 18 metabolites in the brain ("neurochemical profile").
The objective of this proposal is to develop new methods for high-field brain MRS (3 to 7
Tesla).
Our main hypothesis is that higher magnetic fields lead to improved spatial and temporal
resolution and improved quantification precision.
Aims
1. To obtain improved "neurochemical profiles" in the brain using single voxel proton MRS
at very high field (3 Tesla to 7 Tesla).
2. To develop new methods for proton magnetic resonance spectroscopic imaging (MRSI) to
obtain metabolic maps at very high field (3 Tesla to 7 Tesla).
Since this project is focused on technical development, only healthy volunteers will be
recruited (no patients).
up to 18 metabolites in the brain ("neurochemical profile").
The objective of this proposal is to develop new methods for high-field brain MRS (3 to 7
Tesla).
Our main hypothesis is that higher magnetic fields lead to improved spatial and temporal
resolution and improved quantification precision.
Aims
1. To obtain improved "neurochemical profiles" in the brain using single voxel proton MRS
at very high field (3 Tesla to 7 Tesla).
2. To develop new methods for proton magnetic resonance spectroscopic imaging (MRSI) to
obtain metabolic maps at very high field (3 Tesla to 7 Tesla).
Since this project is focused on technical development, only healthy volunteers will be
recruited (no patients).
Inclusion Criteria:
- over 18 years old
Exclusion Criteria:
- no metallic implant or other MRI-incompatible device
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