Imaging Characteristics of a Follow-up 18F-AV-1451 Scan
| Status: | Completed |
|---|---|
| Conditions: | Alzheimer Disease |
| Therapuetic Areas: | Neurology |
| Healthy: | No |
| Age Range: | 50 - Any |
| Updated: | 2/10/2017 |
| Start Date: | May 2014 |
| End Date: | December 2016 |
An Open Label, Multicenter Study, Evaluating the Imaging Characteristics of a Follow-up 18F-AV-1451 Scan in Subjects Who Have Had a Prior 18F-AV-1451 Scan
This study will evaluate the imaging characteristics of 18F-AV-1451 in subjects with a
previous 18F-AV-1451 scan in order to assess the rate of change of tau deposition over time.
previous 18F-AV-1451 scan in order to assess the rate of change of tau deposition over time.
Inclusion Criteria:
- Have a previous 18F-AV-1451 brain scan
- Can tolerate up to two Positron Emission Tomography (PET) imaging sessions and a
Magnetic Resonance Imaging (MRI) scan
- Ability to provide informed consent
Exclusion Criteria:
- Current clinically significant psychiatric disease
- Are claustrophobic
- Current clinically significant cardiovascular disease or ECG abnormalities, or
additional risk factors for Torsades de Pointes
- Current clinically significant infectious disease, endocrine or metabolic disease,
pulmonary, renal or hepatic impairment, or cancer
- Females of childbearing potential who are not surgically sterile, not refraining from
sexual activity or not using reliable methods of contraception
- Have had a non-study related radiopharmaceutical imaging or treatment procedure
within 7 days prior to the study imaging session
We found this trial at
4
sites
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St. Louis, Missouri 63110
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