Minocycline to Reduce Pain After Carpal Tunnel Release
| Status: | Completed |
|---|---|
| Conditions: | Chronic Pain, Chronic Pain, Post-Surgical Pain, Hospital, Orthopedic |
| Therapuetic Areas: | Musculoskeletal, Orthopedics / Podiatry, Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 6/13/2018 |
| Start Date: | January 2012 |
| End Date: | April 2014 |
A Trial of Minocycline for Pain After Carpal Tunnel and Trigger Release
The investigators are looking at whether peri-operative minocycline will reduce the duration
of pain after minor hand surgery: carpal tunnel release and trigger finger release.
The investigators' hypothesis is that minocycline will reduce post-operative pain.
of pain after minor hand surgery: carpal tunnel release and trigger finger release.
The investigators' hypothesis is that minocycline will reduce post-operative pain.
This is a double blinded randomized controlled trial. Patients are given 100mg of minocycline
2 hours prior to their procedure and then 100mg two times a day for 5 days. The subjects are
then contacted daily to check their level of pain. The investigators' outcome of interest is
time to pain resolution.
The investigators will perform a futility analysis to assess if a larger trial would be a
reasonable next step after this pilot study.
2 hours prior to their procedure and then 100mg two times a day for 5 days. The subjects are
then contacted daily to check their level of pain. The investigators' outcome of interest is
time to pain resolution.
The investigators will perform a futility analysis to assess if a larger trial would be a
reasonable next step after this pilot study.
Inclusion Criteria:
- Adult, Veteran,
Exclusion Criteria:
- Kidney failure, Liver failure, thrombocytopenia, ALS, SLE, Frailty, unable to
understand survery
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