Comparative Study Using Dermabrasion vs CO2 Laser & Collagen Dressing vs Vaseline Gauze in MKTP
| Status: | Recruiting |
|---|---|
| Conditions: | Dermatology, Dermatology |
| Therapuetic Areas: | Dermatology / Plastic Surgery |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 2/24/2017 |
| Start Date: | January 2014 |
| End Date: | July 2019 |
| Contact: | Tasneem Mohammad, MD |
| Phone: | 313-916-6964 |
Prospective Open Label Parallel Study Comparing Use of Carbon Dioxide Laser Versus Dermabrasion for Denuding Epithelium and Collagen Dressing Versus Vaseline Impregnated Gauze for the Melanocyte Keratinocyte Transplant Procedure
The purpose of this study is to:
1. Compare two different techniques in the melanocyte keratinocyte transplant procedure:
Use of carbon dioxide laser versus use of dermabrasion
2. Compare two different dressings in the melanocyte keratinocyte transplant procedure:
vaseline impregnated gauze versus collagen dressing
1. Compare two different techniques in the melanocyte keratinocyte transplant procedure:
Use of carbon dioxide laser versus use of dermabrasion
2. Compare two different dressings in the melanocyte keratinocyte transplant procedure:
vaseline impregnated gauze versus collagen dressing
The melanocyte keratinocyte transplant procedure (MKTP) has been shown to be effective in
treating vitiligo and other conditions with depigmented skin. MKTP involves the
transplantation of melanocytes and keratinocytes from normal skin onto the depigmented skin
in order to repigment the skin.
Both dermabrasion and carbon dioxide lasers have been used effectively in MKTP to denude the
epithelium. This study will compare the efficacy of these two techniques.
The study will also compare the efficacy of two different dressings used in MKTP, vaseline
impregnated gauze and collagen dressings.
treating vitiligo and other conditions with depigmented skin. MKTP involves the
transplantation of melanocytes and keratinocytes from normal skin onto the depigmented skin
in order to repigment the skin.
Both dermabrasion and carbon dioxide lasers have been used effectively in MKTP to denude the
epithelium. This study will compare the efficacy of these two techniques.
The study will also compare the efficacy of two different dressings used in MKTP, vaseline
impregnated gauze and collagen dressings.
Inclusion Criteria:
- Depigmented patches of skin
Exclusion Criteria:
- History of Acral Vitiligo
- Unstable Vitiligo, defined as new areas of depigmentation or enlarging areas of
depigmentation within the last 6 months
- History of hypertrophic scarring or keloids
- History of koebnerization (new patches of vitiligo at sites of injury or trauma)
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