Metabolic Responses to Bariatric Surgery



Status:Recruiting
Conditions:Obesity Weight Loss
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:18 - 65
Updated:7/20/2018
Start Date:February 2011
End Date:June 2019
Contact:Mohamed R Ali, MD
Email:mrali@ucdavis.edu
Phone:916-734-7290

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Genetic and Biochemical Characteristics of Medically-Complicated Obesity and Response to Bariatric Surgery

Research the genetic and biomechanical markers of human adipose tissue on patients with
morbid obesity. Additional tissue/fluid collection is also gathered during the time of
surgery.

Study participation by invitation. Patients will be invited to participate after completing
all necessary clinical visits including lab studies, counseling, and participation in
educational programs. During the pre-operative visit patients interested in participation
will complete all necessary consent documentation, during surgery tissue collection will
include subcutaneous & omental fat, jejunum (Gastric Bypass), gastric remnant (sleeve
gastrectomy), and liver biopsy. Post surgery patient will be observed for weight loss and
resolution of co-morbidities. At designated times post surgery when lab studies are ordered
additional blood/urine samples will be collected and analyzed.

Inclusion Criteria:

- Meet NIH Criteria for Bariatric Surgery

- Between the Age of 18-65

- Dyslipidemia controlled with medication

- Impaired glucose metabolism or type 2 diabetes

Exclusion Criteria:

- Uncontrolled Metabolic syndrome (uncontrolled diabetes, htn, dyslipidemia), one or all
conditions.
We found this trial at
1
site
2315 Stockton Blvd.
Sacramento, California 95817
(916) 734-2011
Principal Investigator: Mohamed R Ali, MD
Phone: 916-734-7820
University of California, Davis Medical Center UC Davis Medical Center serves a 65,000-square-mile area that...
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mi
from
Sacramento, CA
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