Deep Brain Stimulation Effects on Gait and Balance in Patients With Parkinson's Disease
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Parkinsons Disease |
| Therapuetic Areas: | Neurology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 1/26/2019 |
| Start Date: | September 2013 |
| End Date: | December 2025 |
Deep Brain Stimulation Effects on Gait and Balance in Patients With Parkinson's Disease.
The purpose of this study is to evaluate the effect of Deep Brain stimulation (DBS) on
walking in patients with Parkinson's disease that have had DBS. While DBS improves
Parkinson's disease (PD) symptoms and walking in many patients in some of the patients
walking problems persist. This study aims to find out what are the best stimulation
parameters of the DBS in order to improve walking.
walking in patients with Parkinson's disease that have had DBS. While DBS improves
Parkinson's disease (PD) symptoms and walking in many patients in some of the patients
walking problems persist. This study aims to find out what are the best stimulation
parameters of the DBS in order to improve walking.
Parkinson disease (PD) is defined by the presence of a resting tremor, slowness, stiffness
and problems with balance and walking. Gait disorder in Parkinson's disease is common and has
a greater impact on quality of life. Currently, carbidopa-levodopa and Deep Brain Stimulation
are the only treatments available for gait impairment.
This study is meant to see if there is improvement in gait or freezing of gait are seen after
changes in the stimulation parameters. Subjects will be randomly assigned to four different
stimulation parameters: both stimulators on (BL ON), both stimulators off (BL OFF), right
stimulator on (R ON), left stimulator on (L ON). The investigators will assess your gait
using a clinical scales as well as wearable sensors attached to your body. Assessments will
be done one hour after each change in the stimulation parameters.
Gait will be studied using wireless sensors attached to the ankles and wrists to determine
speed, stride length and turning time.
and problems with balance and walking. Gait disorder in Parkinson's disease is common and has
a greater impact on quality of life. Currently, carbidopa-levodopa and Deep Brain Stimulation
are the only treatments available for gait impairment.
This study is meant to see if there is improvement in gait or freezing of gait are seen after
changes in the stimulation parameters. Subjects will be randomly assigned to four different
stimulation parameters: both stimulators on (BL ON), both stimulators off (BL OFF), right
stimulator on (R ON), left stimulator on (L ON). The investigators will assess your gait
using a clinical scales as well as wearable sensors attached to your body. Assessments will
be done one hour after each change in the stimulation parameters.
Gait will be studied using wireless sensors attached to the ankles and wrists to determine
speed, stride length and turning time.
Inclusion Criteria:
- Parkinson's disease stage 1-3
- walking impairment
•Exclusion Criteria:
- stage 4,5
- dementia
We found this trial at
1
site
Miami, Florida 33124
(305) 284-2211
Principal Investigator: Corneliu Luca, MD PhD
Phone: 305-243-2781
University of Miami A private research university with more than 15,000 students from around the...
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