High Fructose Corn Syrup



Status:Recruiting
Conditions:Obesity Weight Loss, Gastrointestinal, Gastrointestinal
Therapuetic Areas:Endocrinology, Gastroenterology
Healthy:No
Age Range:18 - 65
Updated:4/2/2016
Start Date:March 2012
End Date:June 2016
Contact:Lynda Bowers, MSEd
Email:lbowers@dom.wustl.edu
Phone:314-362-0590

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The Effect of High Fructose Corn Syrup Feeding in Nonalcoholic Fatty Liver Disease

The purpose of this research study is to learn more about high fructose corn syrup, a sugar
used to sweeten drinks and foods, affects metabolism in obese persons with and without
nonalcoholic fatty liver disease. Eligible participants will be studied before and after
eating a diet high in high fructose corn syrup or a a standard diet (low in high fructose
corn syrup) for four weeks.


Inclusion Criteria:

- IHTG >10% or <5%

- BMI 30.0-45.0 kg/m2

- Sedentary

- Consume <10% calories from high fructose corn syrup

- Weight stable for previous 3 months

Exclusion Criteria:

- IHTG 5.1-9.9%

- Children

- Adults over 65 years

- Pregnant

- Lactating

- Exercise >1.5 hours/week

- Hepatitis B or C

- Diabetes

- History of liver disease

- History of alcohol abuse

- Severe hypertriglyceridemia (>300 mg/dl)

- Smokers

- Anemia (Hemoglobin <10mg/dl)

- Not weight stable
We found this trial at
1
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St. Louis, Missouri 63108
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St. Louis, MO
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