An Adaptive Treatment Strategy for Adolescent Depression-Continuation
| Status: | Completed |
|---|---|
| Conditions: | Depression, Depression |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 12 - 17 |
| Updated: | 3/23/2019 |
| Start Date: | June 2012 |
| End Date: | October 1, 2018 |
A Personalized Approach to Achieving a Sustained Response to Treatment for Adolescent Depression
The purpose of the study is:
1. To find out how long teenagers getting talk therapy (interpersonal psychotherapy) for
depression should get therapy before the therapist decides whether or not the teenager
is improving enough, and
2. To compare two ways of providing treatment to teenagers who have not improved enough.
1. To find out how long teenagers getting talk therapy (interpersonal psychotherapy) for
depression should get therapy before the therapist decides whether or not the teenager
is improving enough, and
2. To compare two ways of providing treatment to teenagers who have not improved enough.
This is a continuation of the study "An Adaptive Treatment Strategy for Adolescent Depression
(PTAD) "
(PTAD) "
Inclusion Criteria:
- Adolescent meets DSM-IV-TR criteria for a diagnosis of Major Depressive Disorder,
Dysthymia, or Depressive Disorder NOS; demonstrate symptoms of depression (CDRS-R >
35); and demonstrate impairment in general functioning (CGAS < 65).
- Adolescents and parents must be English-speaking
Exclusion Criteria:
- Adolescent meets criteria for a diagnosis of Schizophrenia, Bipolar Disorder,
Psychosis, Substance Abuse, OCD, Conduct Disorder, Eating Disorder, PDD, or Mental
Retardation.
- Depressed adolescents who are actively suicidal with a plan and/or intent
- Adolescent that are already receiving treatment for depression or if they are taking
medication for a psychiatric diagnosis other than ADHD. Depressed adolescents with a
comorbid diagnosis of ADHD who are on a stable dose of stimulant medication (> 3
months) will be eligible to participate in the studies.
- Adolescent that have already received an adequate trial of IPT-A or fluoxetine.
- Female adolescents who are pregnant, breastfeeding, or having unprotected sexual
intercourse.
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