Randomized Trial of Outpatient vs. Inpatient Management of Low-risk Patients With Upper Gastrointestinal Bleeding.
| Status: | Recruiting |
|---|---|
| Conditions: | Gastrointestinal |
| Therapuetic Areas: | Gastroenterology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | December 2013 |
| End Date: | April 2017 |
| Contact: | Loren Laine, MD |
| Email: | loren.laine@yale.edu |
| Phone: | 203-937-3462 |
Patients presenting to the emergency room with upper gastrointestinal bleeding and a Glasgow
Blatchford score of zero will be randomly assigned to further care in the inpatient vs.
outpatient setting. The hypothesis of this study is that patients who are managed as
outpatients will require interventions at a rate not higher than those managed as inpatients
and will have lower direct healthcare costs.
Blatchford score of zero will be randomly assigned to further care in the inpatient vs.
outpatient setting. The hypothesis of this study is that patients who are managed as
outpatients will require interventions at a rate not higher than those managed as inpatients
and will have lower direct healthcare costs.
Inclusion Criteria:
1. Blood Urea Nitrogen < 18.2 mg/dl
2. Hemoglobin ≥ 13.0 g/dl for men and ≥ 12.0 g/dl for women
3. Systolic blood pressure ≥ 110 mm Hg
4. Heart rate < 100 beats/min
Exclusion Criteria:
1. Inability to obtain informed consent
2. Pregnancy
3. History of liver disease
4. History of heart failure
5. Syncope that is temporally related to ongoing bleeding
6. Melena
7. Contraindication to proton pump inhibitor use
8. Other conditions that necessitate inpatient evaluation.
9. Inpatients with new onset of GI bleeding
We found this trial at
1
site
20 York St, N20 York St,
New Haven, Connecticut 06520
New Haven, Connecticut 06520
(203) 688-4242
Phone: 203-937-3462
Yale-New Haven Hospital Relying on the skill and expertise of more than 4,500 university and...
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