Brexpiprazole as an Additional Treatment to Paroxetine or Sertraline in Adult Patients Suffering From Post-traumatic Stress Disorder (PTSD)



Status:Terminated
Conditions:Psychiatric, Psychiatric, Psychiatric
Therapuetic Areas:Psychiatry / Psychology
Healthy:No
Age Range:18 - 65
Updated:4/21/2016
Start Date:December 2013
End Date:October 2015

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Trial Summary
Trial Overview
Inclusion Criteria

Interventional, Randomised, Double-blind, Parallel-group, Placebo-controlled, Flexible-dose Study of Brexpiprazole as Adjunctive Treatment to Paroxetine or Sertraline in Adult Patients Suffering From Post-traumatic Stress Disorder (PTSD)

To evaluate the efficacy of brexpiprazole as adjunctive treatment to paroxetine or
sertraline on PTSD symptoms.


Inclusion Criteria:

- The patient has PTSD, diagnosed according to DSM-IV-TR™ and confirmed by the Mini
International Neuropsychiatric Interview (MINI).

- The patient has a pre-defined Clinician-Administered PTSD Scale Part 2 (CAPS-2) total
score at Screening and Baseline Visits.

- The reported duration of the PTSD is at least 3 months.

Exclusion Criteria:

- The index traumatic event that led to development of PTSD took place more than 15
years before screening.

- The patient has a severe personality disorder that in the investigator's opinion may
interfere with the conduct of the study.

- The patient is at significant suicidal risk.

Other inclusion and exclusion criteria may apply.
We found this trial at
23
sites
US006
Gainesville, Florida 32607
713
mi
from 43215
Gainesville, FL
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US003
Austin, Texas 78731
1065
mi
from 43215
Austin, TX
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US002
Bradenton, Florida 34201
868
mi
from 43215
Bradenton, FL
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US001
Bronx, New York 10467
485
mi
from 43215
Bronx, NY
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US009
Cincinnati, Ohio 45219
94
mi
from 43215
Cincinnati, OH
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US005
Dayton, Ohio 45417
69
mi
from 43215
Dayton, OH
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US012
Indianapolis, Indiana 46260
167
mi
from 43215
Indianapolis, IN
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US016
Jacksonville, Florida 32256
678
mi
from 43215
Jacksonville, FL
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US019
Las Vegas, Nevada 89102
1759
mi
from 43215
Las Vegas, NV
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US004
Los Angeles, California 90024
1982
mi
from 43215
Los Angeles, CA
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US025
Los Angeles, California 90102
1972
mi
from 43215
Los Angeles, CA
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US011
Memphis, Tennessee 38119
508
mi
from 43215
Memphis, TN
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US007
Nashua, New Hampshire 03060
629
mi
from 43215
Nashua, NH
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US014
Norristown, Pennsylvania 19403
406
mi
from 43215
Norristown, PA
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US020
North Miami, Florida 33161
986
mi
from 43215
North Miami, FL
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US010
Portland, Oregon 97210
2026
mi
from 43215
Portland, OR
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US024
Riverside, California 92504
1929
mi
from 43215
Riverside, CA
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US021
21 Roslindale Avenue
Roslindale, Massachusetts 02131
638
mi
from 43215
Roslindale, MA
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US008
San Diego, California 92123
1947
mi
from 43215
San Diego, CA
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US015
San Diego, California 90103
1951
mi
from 43215
San Diego, CA
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US026
Seattle, Washington 98104
2006
mi
from 43215
Seattle, WA
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EE001
Tallinn,
4440
mi
from 43215
Tallinn,
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US017
Tampa, Florida 33609
831
mi
from 43215
Tampa, FL
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