Suitability of DCE-MRI for Detection of Vascular Changes After VBT



Status:Recruiting
Conditions:Women's Studies
Therapuetic Areas:Reproductive
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:October 2013
Contact:Lilie Lin, MD
Email:PennCancerTrials@emergingmed.com
Phone:855-216-0098

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A Pilot Study to Assess the Suitability of DCE-MRI for Detection of Vascular Changes After Vaginal Brachytherapy

This is a pilot study of DCE MR imaging to detect vascular changes in the vagina during and
after radiotherapy n patients receiving adjuvant brachytherapyfor cervical or endometrial
cancer.


Inclusion Criteria:

- Must be 18 years of age.

- Must have histologically confirmed carcinoma of the cervix, carcinoma or
carcinosarcoma of the uterus.

- Subjects are receiving intracavitary brachytherapy.

- ECOG performance status of 0-2.

- Creatinine clearance 30.

Exclusion Criteria:

- Subjects with an inability to tolerate MR imaging (i.e. claustrphobia)

- Study subjects who have contraindication to MRI scanning such as but not limited to
subjects with pacemakers, metal fragments in the eye or certain metallic implants.

- Patients who do not speak or read English.
We found this trial at
1
site
3400 Civic Center Blvd
Philadelphia, Pennsylvania 19104
(215) 662-6065
Principal Investigator: Lilie Lin, MD
Phone: 855-216-0098
Abramson Cancer Center of the University of Pennsylvania The Abramson Cancer Center of the University...
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mi
from
Philadelphia, PA
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