Model-Based Image Reconstruction for X-Ray CT in Lung Imaging
| Status: | Completed |
|---|---|
| Conditions: | Pulmonary |
| Therapuetic Areas: | Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | August 2010 |
| End Date: | December 2015 |
To develop a computer program that will improve CT image quality and decrease the amount of
x-ray radiation that future patients may be exposed to when they have a CT examination.
x-ray radiation that future patients may be exposed to when they have a CT examination.
We will be asking patients for their permission to save and use the sinogram from their CT
scan. The sinogram will be de-identified and sent to an archive system for storage. It will
be exported to a computer for processing using MBIR (model based iterative reconstruction).
MBIR (model based iterative reconstruction) is a new method being developed to process CT
sinograms. The newly reconstructed images will be reviewed by experts to determine if they
are as readable and accurate as CT images created with the software that is currently being
used. Sinogram data and the reconstructed images will be shared with collaborating
researchers at General Electric Global Research.
scan. The sinogram will be de-identified and sent to an archive system for storage. It will
be exported to a computer for processing using MBIR (model based iterative reconstruction).
MBIR (model based iterative reconstruction) is a new method being developed to process CT
sinograms. The newly reconstructed images will be reviewed by experts to determine if they
are as readable and accurate as CT images created with the software that is currently being
used. Sinogram data and the reconstructed images will be shared with collaborating
researchers at General Electric Global Research.
Inclusion Criteria:
1. 18 years of age and older 2. No medical or psychiatric condition precluding informed
consent
Exclusion Criteria:
1. Inability to lie flat on the back with arms raised over the head for 30min.
2. Metallic implants or metallic devices in the chest or back.
3. Participation in other research trials involving ionizing radiation
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