Laser Therapy Treatment of Peri-implantitis.

Inclusion Criteria:

- Patients, aged 18 - 85 years

- Physical status according to the American Society of Anesthesiologists (ASA) I or II,
which includes patients who are systemically healthy or suffer under mild to
moderate, but well controlled systemic diseases.

- Patients having a minimum of 1 dental implant with peri-implantitis.

- The dental implant with peri-implantitis has ≥ 3 threads exposed or pocket probing
depth (PPD) ≥ 5mm, with bleeding on probing (BOP) and/or suppuration (pus).

- The implants are in function for at least 6 months

- No uncontrolled systemic disease or condition known to alter bone metabolism, like
Osteoporosis, Osteopenia, Hyperparathyroidism, Paget's disease.

- Only rough surface implant will be included in this study

Exclusion Criteria:

- Long-term use of antibiotics > 2 weeks in the past two months

- No peri-implantitis treatment in the last 2 months

- Patients taking medications known to modify bone metabolism (such as bisphosphonates,
corticosteroids, Hormone replacement therapy for menopausal women, Parathyroid
hormone, Denosumab, strontium ranelate).

- Pregnant females or those planning to become pregnant.

- Patients with a history of medically diagnosed oral cancer, bisphosphonate usage,
Sepsis or those having adverse outcomes to oral procedures in the past, will be
excluded

- Mobility of dental implants

- History of alcoholism or drug abuse

- Current smokers or quit smoking less than 6 months

- Diseases of the immune system or any medical condition that may influence the outcome
(uncontrolled diabetes (HbA1c >7)

- Patients with allergies known to affect one or more of the treatment provided in this
study

- Polish surface implants

- Implants with trabecular surface