S1204, Viral Screening in Newly Diagnosed Cancer Patients



Status:Active, not recruiting
Conditions:Cancer, Cancer, HIV / AIDS, HIV / AIDS
Therapuetic Areas:Immunology / Infectious Diseases, Oncology
Healthy:No
Age Range:18 - Any
Updated:2/23/2019
Start Date:August 29, 2013
End Date:February 2021

Use our guide to learn which trials are right for you!

A Sero-Epidemiologic Survey and Cost Effectiveness Study of Screening for Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) Among Newly Diagnosed Cancer Patients

The goal of this study is to estimate the prevalence of HIV, Hepatitis B and hepatitis C
infection among newly diagnosed cancer patients presenting to community and academic oncology
clinics.

Primary Objective

Among newly diagnosed cancer patients presenting to SWOG-affiliated community and academic
oncology clinics, estimate the prevalence of human immunodeficiency virus (HIV), hepatitis B
(HBV), and hepatitis C (HCV) infection. Prevalence estimates will be further stratified: by
whether infection with the virus(es) is known, as reported by patients and/or their physician
prior to study testing, vs. unknown; by presenting cancer type, and by self-reported risk
factors for each virus.

Secondary Objectives

- Evaluate known sociodemographic, clinical, and behavioral factors that are significantly
associated with previously undiagnosed HIV, HBV, and/or HCV infection in a population of
people with newly diagnosed cancer.

- Among patients who are identified as having HIV, HBV, and/or HCV, evaluate the timing
and type of treatments received, both for the viral infections and the cancers.

- Evaluate type and rate of cancer treatment-related adverse events in patients with HIV,
HBV, and/or HCV infection.

- Using simulation modeling that is directly informed by the data obtained from this
study, determine the cost-effectiveness (expressed as cost per infection detected and
cost per year of life gained) of (1) routine, universal screening and (2) risk
factor-directed screening of newly diagnosed cancer patients for HIV, HBV, and/or HCV
vs. current care.

Tertiary Objective

Create a biorepository of stored serum for future translational medicine studies that may
include identifying genomic and viral factors that increase the risk of serious adverse
effects among participants infected with HIV, HBV, and/or HCV being treated for invasive
cancers.

Inclusion Criteria:

- presenting for evaluation or treatment of a new cancer malignancy(including
hematologic)

- confirmed pathologic diagnosis must be within 120 days of registration (Patients
presenting for "second opinions" of confirmed malignancies are eligible, including
those who have started cancer treatment at other facilities)

- at least 18 years of age

- patient must have had their blood drawn for HIV, HBV and HCV testing prior to
registration (Patients who have had HIV, HBV and/or HCV testing within 60 days prior
to registration and who do not wish to be retested are eligible, provided supporting
documents can be obtained confirming viral test results for all three viruses.
Documentation must be obtained prior to registration.

Patients who are viral positive for either HIV, HBV, and/or HCV and who do not wish to be
retested are eligible, provided documentation of viral load within 120 days prior to
registration can be obtained. Note that these patients must be tested for or provide
current viral load for all three viruses to be eligible. Documentation must be obtained
prior to registration.)

- Patients must sign and give written informed consent in accordance with institutional
and federal guidelines

- Patients must be offered the opportunity to allow their blood specimens to be banked
by the SWOG Repository for future research

Exclusion Criteria:

- diagnosed with a malignancy other than the current malignancy within the past five
years (with the exception of basal cell or squamous cell skin cancer, in situ cervical
cancer, or in situ breast cancer.)
We found this trial at
58
sites
1 Quality Dr
Vacaville, California 95688
(707) 624-4000
Principal Investigator: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente Medical Center - Vacaville First established in Vallejo in 1945, Kaiser Permanente Napa-Solano...
?
mi
from
Vacaville, CA
Click here to add this to my saved trials
4502 Medical Drive
San Antonio, Texas 78284
(210) 567-7000
Principal Investigator: Laura L. Tenner
Phone: 210-450-3800
University of Texas Health Science Center at San Antonio The University of Texas Health Science...
?
mi
from
San Antonio, TX
Click here to add this to my saved trials
Amarillo, Texas 79106
Principal Investigator: Suhasini (Sue) Nadesan
Phone: 806-359-4673
?
mi
from
Amarillo, TX
Click here to add this to my saved trials
Baton Rouge, Louisiana 70805
Principal Investigator: Augusto C. Ochoa
Phone: 504-568-2428
?
mi
from
Baton Rouge, LA
Click here to add this to my saved trials
Baton Rouge, Louisiana 70809
Principal Investigator: Augusto C. Ochoa
Phone: 504-568-2428
?
mi
from
Baton Rouge, LA
Click here to add this to my saved trials
Baton Rouge, Louisiana 70809
Principal Investigator: Augusto C. Ochoa
Phone: 504-568-2428
?
mi
from
Baton Rouge, LA
Click here to add this to my saved trials
Baton Rouge, Louisiana 70809
Principal Investigator: Augusto C. Ochoa
Phone: 504-568-2428
?
mi
from
Baton Rouge, LA
Click here to add this to my saved trials
Berwyn, Illinois 60402
Principal Investigator: Irene Q. Ma
Phone: 708-484-8400
?
mi
from
Berwyn, IL
Click here to add this to my saved trials
Billings, Montana 59101
Principal Investigator: Benjamin T. Marchello
Phone: 800-648-6274
?
mi
from
Billings, MT
Click here to add this to my saved trials
Boston, Massachusetts 02118
Principal Investigator: Timothy P. Cooley
Phone: 617-638-8265
?
mi
from
Boston, MA
Click here to add this to my saved trials
400 South Clark Street
Butte, Montana 59701
406-723-2500
Saint James Community Hospital and Cancer Treatment Center St. James Healthcare has played an important...
?
mi
from
Butte, MT
Click here to add this to my saved trials
Chicago, Illinois 60640
Principal Investigator: Stuart A. Krauss
Phone: 773-564-5044
?
mi
from
Chicago, IL
Click here to add this to my saved trials
272 Hospital Rd
Chillicothe, Ohio 45601
740-779-7500
Principal Investigator: John P. Kuebler
Phone: 614-488-2745
Adena Regional Medical Center Since 1895, Adena Health System has remained focused on its commitment...
?
mi
from
Chillicothe, OH
Click here to add this to my saved trials
810 Jasonway Avenue
Columbus, Ohio 43214
614/442-3130
Principal Investigator: John P. Kuebler
Phone: 614-488-2745
Columbus Oncology and Hematology Associates Inc Columbus Oncology and Hematology Associates is a group of...
?
mi
from
Columbus, OH
Click here to add this to my saved trials
111 S Grant Ave
Columbus, Ohio 43215
(614) 566-9000
Principal Investigator: John P. Kuebler
Phone: 614-488-2745
Grant Medical Center Founded in 1900 in Columbus' downtown, Grant has grown into one of...
?
mi
from
Columbus, OH
Click here to add this to my saved trials
Covington, Louisiana 70433
Principal Investigator: Augusto C. Ochoa
Phone: 504-568-2428
?
mi
from
Covington, LA
Click here to add this to my saved trials
Covington, Louisiana 70433
Principal Investigator: Augusto C. Ochoa
Phone: 504-568-2428
?
mi
from
Covington, LA
Click here to add this to my saved trials
Fontana, California 92335
Principal Investigator: Han A. Koh
Phone: 626-564-3455
?
mi
from
Fontana, CA
Click here to add this to my saved trials
701 Grove Rd
Greenville, South Carolina 29605
(864) 455-7000
Principal Investigator: Mark A. O'Rourke
Phone: 864-241-6251
Greenville Memorial Hospital Greenville Memorial Medical Campus is a regional referral center for the diagnosis...
?
mi
from
Greenville, SC
Click here to add this to my saved trials
Greenville, South Carolina 29601
?
mi
from
Greenville, SC
Click here to add this to my saved trials
Greenville, South Carolina 29605
Principal Investigator: Mark A. O'Rourke
Phone: 864-241-6251
?
mi
from
Greenville, SC
Click here to add this to my saved trials
Greenville, South Carolina 29605
?
mi
from
Greenville, SC
Click here to add this to my saved trials
Greenville, South Carolina 29615
?
mi
from
Greenville, SC
Click here to add this to my saved trials
?
mi
from
Greer, SC
Click here to add this to my saved trials
Harbor City, California 90710
Principal Investigator: Han A. Koh
Phone: 626-564-3455
?
mi
from
Harbor City, CA
Click here to add this to my saved trials
Hines, Illinois 60141
Principal Investigator: Elizabeth Henry
Phone: 708-226-4357
?
mi
from
Hines, IL
Click here to add this to my saved trials
1 Jarrett White Rd
Honolulu, Hawaii 96859
(808) 433-6661
Principal Investigator: Jeffrey L. Berenberg
Phone: 808-524-6115
Tripler Army Medical Center The attack of Pearl Harbor led to the construction of Tripler...
?
mi
from
Honolulu, HI
Click here to add this to my saved trials
Honolulu, Hawaii 96813
Principal Investigator: Scott D. Ramsey
Phone: 206-667-7846
?
mi
from
Honolulu, HI
Click here to add this to my saved trials
Houma, Louisiana 70360
Principal Investigator: Augusto C. Ochoa
Phone: 504-568-2428
?
mi
from
Houma, LA
Click here to add this to my saved trials
Houma, Louisiana 70360
Principal Investigator: Augusto C. Ochoa
Phone: 504-568-2428
?
mi
from
Houma, LA
Click here to add this to my saved trials
Houston, Texas 77030
Principal Investigator: Nishin Bhadkamkar
Phone: 713-792-3245
?
mi
from
Houston, TX
Click here to add this to my saved trials
Kansas City, Missouri 64218
Principal Investigator: Chao H. Huang
Phone: 913-945-7552
?
mi
from
Kansas City, MO
Click here to add this to my saved trials
4101 South 4th Street
Leavenworth, Kansas 66048
Principal Investigator: Ace Allen
Phone: 800-525-1483
?
mi
from
Leavenworth, KS
Click here to add this to my saved trials
Lone Tree, Colorado 80124
?
mi
from
Lone Tree, CO
Click here to add this to my saved trials
Marion, Ohio 43302
Principal Investigator: John P. Kuebler
Phone: 614-488-2745
?
mi
from
Marion, OH
Click here to add this to my saved trials
2500 Alhambra Ave
Martinez, California 94553
(925) 370-5000
Principal Investigator: James H. Feusner
Phone: 510-450-7600
Contra Costa Regional Medical Center Contra Costa Health Services is the largest department of County...
?
mi
from
Martinez, CA
Click here to add this to my saved trials
Meridian, Idaho 83642
Principal Investigator: Benjamin B. Bridges
Phone: 800-845-4624
?
mi
from
Meridian, ID
Click here to add this to my saved trials
Metairie, Louisiana 70006
Principal Investigator: Augusto C. Ochoa
Phone: 504-568-2428
?
mi
from
Metairie, LA
Click here to add this to my saved trials
Monroe, Louisiana 71202
Principal Investigator: Gary V. Burton
Phone: 318-813-1412
?
mi
from
Monroe, LA
Click here to add this to my saved trials
1330 Coshocton Ave
Mount Vernon, Ohio 43050
(740) 393-9000
Principal Investigator: John P. Kuebler
Phone: 614-488-2745
Knox Community Hospital A community-owned, 115-bed, not-for-profit hospital located in Mount Vernon, Ohio (approximately 40...
?
mi
from
Mount Vernon, OH
Click here to add this to my saved trials
New Orleans, Louisiana 70112
Principal Investigator: Augusto C. Ochoa
Phone: 504-568-2428
?
mi
from
New Orleans, LA
Click here to add this to my saved trials
New York, New York 10032
Principal Investigator: Melissa K. Accordino
Phone: 212-305-8615
?
mi
from
New York, NY
Click here to add this to my saved trials
1320 W Main St
Newark, Ohio 43055
(740) 348-4000
Licking Memorial Hospital Licking Memorial Health Systems (LMHS) is a not-for-profit health care organization dedicated...
?
mi
from
Newark, OH
Click here to add this to my saved trials
Oakland, California 94609
Principal Investigator: Milana V. Dolezal
Phone: 415-209-2686
?
mi
from
Oakland, CA
Click here to add this to my saved trials
Oakland, California 94611
Principal Investigator: Louis Fehrenbacher
Phone: 626-564-3455
?
mi
from
Oakland, CA
Click here to add this to my saved trials
Palm Springs, California 92262
Principal Investigator: Elber S. Camacho
Phone: 760-416-4730
?
mi
from
Palm Springs, CA
Click here to add this to my saved trials
Panorama City, California 91402
Principal Investigator: Han A. Koh
Phone: 626-564-3455
?
mi
from
Panorama City, CA
Click here to add this to my saved trials
Portland, Oregon 97227
Principal Investigator: Sandeep H. Mashru
Phone: 503-335-2400
?
mi
from
Portland, OR
Click here to add this to my saved trials
1805 27th St
Portsmouth, Ohio 45662
(740) 356-5000
Principal Investigator: John P. Kuebler
Phone: 614-488-2745
Southern Ohio Medical Center Southern Ohio Medical Center (SOMC) is a 222-bed 501(C)(3) not-for-profit hospital...
?
mi
from
Portsmouth, OH
Click here to add this to my saved trials
River Forest, Illinois 60305
Principal Investigator: Isoken Koko
Phone: 708-488-0882
?
mi
from
River Forest, IL
Click here to add this to my saved trials
Roseville, California 95678
Principal Investigator: Louis Fehrenbacher
Phone: 626-564-3455
?
mi
from
Roseville, CA
Click here to add this to my saved trials
San Antonio, Texas 78209
Principal Investigator: Laura L. Tenner
Phone: 210-450-3800
?
mi
from
San Antonio, TX
Click here to add this to my saved trials
San Francisco, California 94115
Principal Investigator: Louis Fehrenbacher
Phone: 626-564-3455
?
mi
from
San Francisco, CA
Click here to add this to my saved trials
Seneca, South Carolina 29672
Principal Investigator: Mark A. O'Rourke
Phone: 864-241-6251
?
mi
from
Seneca, SC
Click here to add this to my saved trials
Shreveport, Louisiana 71103
Principal Investigator: Gary V. Burton
Phone: 318-813-1412
?
mi
from
Shreveport, LA
Click here to add this to my saved trials
Slidell, Louisiana 70458
Principal Investigator: Augusto C. Ochoa
Phone: 504-568-2428
?
mi
from
Slidell, LA
Click here to add this to my saved trials
Spartanburg, South Carolina 29307
Principal Investigator: Mark A. O'Rourke
Phone: 864-241-6251
?
mi
from
Spartanburg, SC
Click here to add this to my saved trials
Topeka, Kansas 66622
Principal Investigator: Ace Allen
Phone: 800-525-1483
?
mi
from
Topeka, KS
Click here to add this to my saved trials